Navigating the clinical landscape of artery of Percheron infarction: A systematic review
Introduction: Infarction of the artery of Percheron (AOP) is a rare vascular condition where a single arterial branch supplies blood to the thalamic and midbrain regions, leading to neurological deficits. The challenge lies in its often-delayed diagnosis due to its rarity and diverse clinical presen...
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Elsevier
2024-12-01
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| Series: | eNeurologicalSci |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405650224000285 |
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| author | Oday Atallah Yasser F. Almealawy Arwa Salam Alabide Minaam Farooq Vivek Sanker Suraa N. Alrubaye Rami Darwazeh Wireko Andrew Awuah Toufik Abdul-Rahman Ahmed Muthana Aalaa Saleh Jack Wellington Amr Badary |
| author_facet | Oday Atallah Yasser F. Almealawy Arwa Salam Alabide Minaam Farooq Vivek Sanker Suraa N. Alrubaye Rami Darwazeh Wireko Andrew Awuah Toufik Abdul-Rahman Ahmed Muthana Aalaa Saleh Jack Wellington Amr Badary |
| author_sort | Oday Atallah |
| collection | DOAJ |
| description | Introduction: Infarction of the artery of Percheron (AOP) is a rare vascular condition where a single arterial branch supplies blood to the thalamic and midbrain regions, leading to neurological deficits. The challenge lies in its often-delayed diagnosis due to its rarity and diverse clinical presentations, necessitating heightened awareness among clinicians for expedited diagnosis and appropriate therapeutic interventions. Materials and methods: All relevant studies involving patients diagnosed with infarction of AOP were retrieved from PubMed, Google Scholar, Web of Science, and Scopus. Only human studies that were published in full English-language reports were included. Included in the search were the terms “Artery of Percheron,” “infarction,” “stroke,” and “demarcation”. Age, gender, presenting symptoms, treatment, recovery time, and outcome of patients with AOP infarction were all recorded. Results: A systematic review was conducted on a total of 530 articles, out of which 130 articles met the specified requirements. The average age is 59, with men comprising 57.7% of the population. The symptoms reported were visual disturbance in 43.9% of cases and changed mental state in 77.2% of cases. Treatment options include conservative management (85.4%), thrombolysis (11.3%), and other approaches. The optimal age range for recovery is between 41 and 50 years old. Conclusion: Our study on acute AOP infarction highlights male predominance, common comorbidities like hypertension and diabetes, and prevalent symptoms including visual disturbance and altered mental state. Early recognition is crucial, with thrombolytic therapy within the critical time window showing promising outcomes. These findings offer insights for enhanced clinical management of AOP infarction. |
| format | Article |
| id | doaj-art-db4ee98f7d494c94ad0c57990bf14da7 |
| institution | OA Journals |
| issn | 2405-6502 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | eNeurologicalSci |
| spelling | doaj-art-db4ee98f7d494c94ad0c57990bf14da72025-08-20T02:05:52ZengElseviereNeurologicalSci2405-65022024-12-013710052110.1016/j.ensci.2024.100521Navigating the clinical landscape of artery of Percheron infarction: A systematic reviewOday Atallah0Yasser F. Almealawy1Arwa Salam Alabide2Minaam Farooq3Vivek Sanker4Suraa N. Alrubaye5Rami Darwazeh6Wireko Andrew Awuah7Toufik Abdul-Rahman8Ahmed Muthana9Aalaa Saleh10Jack Wellington11Amr Badary12Departemnt of Neurosurgery, Hannover Medical School, Hannover, Germany; Corresponding author.Faculty of medicine, University of Kufa, Kufa, IraqFacility of medicine, Al_Kufa university, Najaf, IraqDepartment of Neurosurgery, King Edward Medical University, Mayo Hospital, Lahore,PakistanDepartment of Neurosurgery, Trivandrum Medical College, Kerala, IndiaCollege of Medicine, University of Babylon, Hilla, IraqNeurosurgery department, Prime Hospital, Dubai, United Arab EmiratesUniversity of Babylon, Hilla, Iraq; Faculty of Medicine, Sumy State University, Sumy, UkraineFaculty of Medicine, Sumy State University, Sumy, UkraineCollege of Medicine, University of Baghdad, Baghdad, IraqFaculty of Medical Sciences, Lebanese University, Beirut, LebanonDepartment of Neurosurgery, Branford TeachingHospital NHS Foundation Trust, Bradford, UKDepartemnt of Neurosurgery, Klinikum Dessau, Dessau-Roßlau, GermanyIntroduction: Infarction of the artery of Percheron (AOP) is a rare vascular condition where a single arterial branch supplies blood to the thalamic and midbrain regions, leading to neurological deficits. The challenge lies in its often-delayed diagnosis due to its rarity and diverse clinical presentations, necessitating heightened awareness among clinicians for expedited diagnosis and appropriate therapeutic interventions. Materials and methods: All relevant studies involving patients diagnosed with infarction of AOP were retrieved from PubMed, Google Scholar, Web of Science, and Scopus. Only human studies that were published in full English-language reports were included. Included in the search were the terms “Artery of Percheron,” “infarction,” “stroke,” and “demarcation”. Age, gender, presenting symptoms, treatment, recovery time, and outcome of patients with AOP infarction were all recorded. Results: A systematic review was conducted on a total of 530 articles, out of which 130 articles met the specified requirements. The average age is 59, with men comprising 57.7% of the population. The symptoms reported were visual disturbance in 43.9% of cases and changed mental state in 77.2% of cases. Treatment options include conservative management (85.4%), thrombolysis (11.3%), and other approaches. The optimal age range for recovery is between 41 and 50 years old. Conclusion: Our study on acute AOP infarction highlights male predominance, common comorbidities like hypertension and diabetes, and prevalent symptoms including visual disturbance and altered mental state. Early recognition is crucial, with thrombolytic therapy within the critical time window showing promising outcomes. These findings offer insights for enhanced clinical management of AOP infarction.http://www.sciencedirect.com/science/article/pii/S2405650224000285Artery of PercheronInfarctionStrokeMidbrainThalamus |
| spellingShingle | Oday Atallah Yasser F. Almealawy Arwa Salam Alabide Minaam Farooq Vivek Sanker Suraa N. Alrubaye Rami Darwazeh Wireko Andrew Awuah Toufik Abdul-Rahman Ahmed Muthana Aalaa Saleh Jack Wellington Amr Badary Navigating the clinical landscape of artery of Percheron infarction: A systematic review eNeurologicalSci Artery of Percheron Infarction Stroke Midbrain Thalamus |
| title | Navigating the clinical landscape of artery of Percheron infarction: A systematic review |
| title_full | Navigating the clinical landscape of artery of Percheron infarction: A systematic review |
| title_fullStr | Navigating the clinical landscape of artery of Percheron infarction: A systematic review |
| title_full_unstemmed | Navigating the clinical landscape of artery of Percheron infarction: A systematic review |
| title_short | Navigating the clinical landscape of artery of Percheron infarction: A systematic review |
| title_sort | navigating the clinical landscape of artery of percheron infarction a systematic review |
| topic | Artery of Percheron Infarction Stroke Midbrain Thalamus |
| url | http://www.sciencedirect.com/science/article/pii/S2405650224000285 |
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