Isolated oculomotor nerve palsy due to mesencephalic infarction diagnosed by ZOOM DWI
Abstract Background Oculomotor nerve palsy is a common neurological presentation in daily practice. Case presentation A 55-year-old man presented with a 3-h history of diplopia and drooping of his bilateral especially left eyelids. Examination revealed an isolated oculomotor nerve palsy consisting o...
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BMC
2025-02-01
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| Series: | BMC Neurology |
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| Online Access: | https://doi.org/10.1186/s12883-025-04021-x |
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| author | Shangpei Wang Yajie Cai Xiaosan Wu Sunhong Yan Longsheng Wang |
| author_facet | Shangpei Wang Yajie Cai Xiaosan Wu Sunhong Yan Longsheng Wang |
| author_sort | Shangpei Wang |
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| description | Abstract Background Oculomotor nerve palsy is a common neurological presentation in daily practice. Case presentation A 55-year-old man presented with a 3-h history of diplopia and drooping of his bilateral especially left eyelids. Examination revealed an isolated oculomotor nerve palsy consisting of left medial rectus, inferior oblique, superior rectus, inferior rectus with intact pupillary reflexes and bilateral especially left superior palpebral levator. Conventional diffusion weighted imaging (DWI) of the brain showed a suspicious restriction in the left midbrain periaqueductal region. If the clinical symptomatology indicates a lesion in the midbrain, of which a high signal intensity was encountered from neurologically healthy older adults, the limited spatial resolution of conventional axial DWI is an enormous disadvantage. Zonally magnified oblique multislice (ZOOM) DWI correlated with apparent diffusion coefficient map providing higher accuracy for accurate diagnosis can identify signal alterations of mesencephalic interpeduncle area. Conclusions This is a rare presentation of isolated oculomotor nerve palsy due to pure mesencephalic infarction especially verified by ZOOM DWI. |
| format | Article |
| id | doaj-art-db4bc12b426a4fbc9f94e2c72b5d4d80 |
| institution | Kabale University |
| issn | 1471-2377 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Neurology |
| spelling | doaj-art-db4bc12b426a4fbc9f94e2c72b5d4d802025-02-09T12:43:05ZengBMCBMC Neurology1471-23772025-02-012511410.1186/s12883-025-04021-xIsolated oculomotor nerve palsy due to mesencephalic infarction diagnosed by ZOOM DWIShangpei Wang0Yajie Cai1Xiaosan Wu2Sunhong Yan3Longsheng Wang4Department of Radiology, the Second Affiliated Hospital of Anhui Medical UniversityDepartment of Radiology, the Second Affiliated Hospital of Anhui Medical UniversityDepartment of Neurology, the Second Affiliated Hospital of Anhui Medical UniversityDepartment of Neurology, the Second Affiliated Hospital of Anhui Medical UniversityDepartment of Radiology, the Second Affiliated Hospital of Anhui Medical UniversityAbstract Background Oculomotor nerve palsy is a common neurological presentation in daily practice. Case presentation A 55-year-old man presented with a 3-h history of diplopia and drooping of his bilateral especially left eyelids. Examination revealed an isolated oculomotor nerve palsy consisting of left medial rectus, inferior oblique, superior rectus, inferior rectus with intact pupillary reflexes and bilateral especially left superior palpebral levator. Conventional diffusion weighted imaging (DWI) of the brain showed a suspicious restriction in the left midbrain periaqueductal region. If the clinical symptomatology indicates a lesion in the midbrain, of which a high signal intensity was encountered from neurologically healthy older adults, the limited spatial resolution of conventional axial DWI is an enormous disadvantage. Zonally magnified oblique multislice (ZOOM) DWI correlated with apparent diffusion coefficient map providing higher accuracy for accurate diagnosis can identify signal alterations of mesencephalic interpeduncle area. Conclusions This is a rare presentation of isolated oculomotor nerve palsy due to pure mesencephalic infarction especially verified by ZOOM DWI.https://doi.org/10.1186/s12883-025-04021-xOculomotor nerve palsyMesencephalic infarctionZOOM DWI |
| spellingShingle | Shangpei Wang Yajie Cai Xiaosan Wu Sunhong Yan Longsheng Wang Isolated oculomotor nerve palsy due to mesencephalic infarction diagnosed by ZOOM DWI BMC Neurology Oculomotor nerve palsy Mesencephalic infarction ZOOM DWI |
| title | Isolated oculomotor nerve palsy due to mesencephalic infarction diagnosed by ZOOM DWI |
| title_full | Isolated oculomotor nerve palsy due to mesencephalic infarction diagnosed by ZOOM DWI |
| title_fullStr | Isolated oculomotor nerve palsy due to mesencephalic infarction diagnosed by ZOOM DWI |
| title_full_unstemmed | Isolated oculomotor nerve palsy due to mesencephalic infarction diagnosed by ZOOM DWI |
| title_short | Isolated oculomotor nerve palsy due to mesencephalic infarction diagnosed by ZOOM DWI |
| title_sort | isolated oculomotor nerve palsy due to mesencephalic infarction diagnosed by zoom dwi |
| topic | Oculomotor nerve palsy Mesencephalic infarction ZOOM DWI |
| url | https://doi.org/10.1186/s12883-025-04021-x |
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