The Effect of Chronic Candesartan Therapy on the Metabolic Profile and Renal Tissue Cytokine Levels in the Obese Zucker Rat

The effect of candesartan, an angiotensin-II type-1 receptor antagonist, on the metabolic profile and renal inflammation is unclear. We evaluated this relationship by feeding male lean (LZ) and obese (OZ) Zucker rats chow or chow with candesartan (23.5 mg/kg⋅diet) for 14 weeks (n=6–8/treatment/body...

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Bibliographic Details
Main Authors:	Carolyn M. Ecelbarger, Arjun Rash, Rajesh K. Sinha, Swasti Tiwari
Format:	Article
Language:	English
Published:	Wiley 2010-01-01
Series:	Mediators of Inflammation
Online Access:	http://dx.doi.org/10.1155/2010/841343
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