INFLUENCE OF S. TYPHI LIPOPOLISACCHARIDE UPON EPITHELIZATION OF SKIN WOUNDS AND EPIDERMAL GROWTH FACTOR SECRETION

Abstract. Influence of topical application of bacterial lipopolysaccharide (LPS), a Toll-like receptor 4 agonist, upon epithelization process was investigated, using a murine incisional skin wound model. It was shown that topical LPS application accelerates wound epithelization, and this process was...

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Main Authors: A. V. Kostarnoy, D. Yu. Logunov, L. V. Verkhovskaya, P. G. Gancheva, B. S. Naroditsky
Format: Article
Language:Russian
Published: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2014-07-01
Series:Медицинская иммунология
Subjects:
Online Access:https://www.mimmun.ru/mimmun/article/view/355
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author A. V. Kostarnoy
D. Yu. Logunov
L. V. Verkhovskaya
P. G. Gancheva
B. S. Naroditsky
author_facet A. V. Kostarnoy
D. Yu. Logunov
L. V. Verkhovskaya
P. G. Gancheva
B. S. Naroditsky
author_sort A. V. Kostarnoy
collection DOAJ
description Abstract. Influence of topical application of bacterial lipopolysaccharide (LPS), a Toll-like receptor 4 agonist, upon epithelization process was investigated, using a murine incisional skin wound model. It was shown that topical LPS application accelerates wound epithelization, and this process was associated with increased levels of epidermal growth factor secretion in wounded skin area.
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institution Kabale University
issn 1563-0625
2313-741X
language Russian
publishDate 2014-07-01
publisher St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists
record_format Article
series Медицинская иммунология
spelling doaj-art-db3263d14fd348dbaad2dd036667588e2025-08-20T04:00:09ZrusSt. Petersburg branch of the Russian Association of Allergologists and Clinical ImmunologistsМедицинская иммунология1563-06252313-741X2014-07-0114322322610.15789/1563-0625-2012-3-223-226352INFLUENCE OF S. TYPHI LIPOPOLISACCHARIDE UPON EPITHELIZATION OF SKIN WOUNDS AND EPIDERMAL GROWTH FACTOR SECRETIONA. V. Kostarnoy0D. Yu. Logunov1L. V. Verkhovskaya2P. G. Gancheva3B. S. Naroditsky4Федеральное Государственное Бюджетное Учреждение «Научно-Исследовательский Институт Эпидемиологии и Микробиологии имени почетного академика Н.Ф. Гамалеи» Министерства здравоохранения и социального развития Российской Федерации, МоскваФедеральное Государственное Бюджетное Учреждение «Научно-Исследовательский Институт Эпидемиологии и Микробиологии имени почетного академика Н.Ф. Гамалеи» Министерства здравоохранения и социального развития Российской Федерации, МоскваФедеральное Государственное Бюджетное Учреждение «Научно-Исследовательский Институт Эпидемиологии и Микробиологии имени почетного академика Н.Ф. Гамалеи» Министерства здравоохранения и социального развития Российской Федерации, МоскваФедеральное Государственное Бюджетное Учреждение «Научно-Исследовательский Институт Эпидемиологии и Микробиологии имени почетного академика Н.Ф. Гамалеи» Министерства здравоохранения и социального развития Российской Федерации, МоскваФедеральное Государственное Бюджетное Учреждение «Научно-Исследовательский Институт Эпидемиологии и Микробиологии имени почетного академика Н.Ф. Гамалеи» Министерства здравоохранения и социального развития Российской Федерации, МоскваAbstract. Influence of topical application of bacterial lipopolysaccharide (LPS), a Toll-like receptor 4 agonist, upon epithelization process was investigated, using a murine incisional skin wound model. It was shown that topical LPS application accelerates wound epithelization, and this process was associated with increased levels of epidermal growth factor secretion in wounded skin area.https://www.mimmun.ru/mimmun/article/view/355bacterial lipopolysaccharidewound healingepithelizationepidermal growth factor
spellingShingle A. V. Kostarnoy
D. Yu. Logunov
L. V. Verkhovskaya
P. G. Gancheva
B. S. Naroditsky
INFLUENCE OF S. TYPHI LIPOPOLISACCHARIDE UPON EPITHELIZATION OF SKIN WOUNDS AND EPIDERMAL GROWTH FACTOR SECRETION
Медицинская иммунология
bacterial lipopolysaccharide
wound healing
epithelization
epidermal growth factor
title INFLUENCE OF S. TYPHI LIPOPOLISACCHARIDE UPON EPITHELIZATION OF SKIN WOUNDS AND EPIDERMAL GROWTH FACTOR SECRETION
title_full INFLUENCE OF S. TYPHI LIPOPOLISACCHARIDE UPON EPITHELIZATION OF SKIN WOUNDS AND EPIDERMAL GROWTH FACTOR SECRETION
title_fullStr INFLUENCE OF S. TYPHI LIPOPOLISACCHARIDE UPON EPITHELIZATION OF SKIN WOUNDS AND EPIDERMAL GROWTH FACTOR SECRETION
title_full_unstemmed INFLUENCE OF S. TYPHI LIPOPOLISACCHARIDE UPON EPITHELIZATION OF SKIN WOUNDS AND EPIDERMAL GROWTH FACTOR SECRETION
title_short INFLUENCE OF S. TYPHI LIPOPOLISACCHARIDE UPON EPITHELIZATION OF SKIN WOUNDS AND EPIDERMAL GROWTH FACTOR SECRETION
title_sort influence of s typhi lipopolisaccharide upon epithelization of skin wounds and epidermal growth factor secretion
topic bacterial lipopolysaccharide
wound healing
epithelization
epidermal growth factor
url https://www.mimmun.ru/mimmun/article/view/355
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