8-Chloro-cAMP-Related Changes on Mice Uteri
Histopathological effects of cAMP analog (8-Chloro-cAMP), tamoxifen, and medroxyprogesterone, alone or combined, upon BALB/c mice uteri are reported. 8-Chloro-cAMP diminished uterine weight, but did not modify its histopathology or estral cycle significantly. Tamoxifen diminished uterine weight show...
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| Format: | Article |
| Language: | English |
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Wiley
2002-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/tsw.2002.282 |
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| _version_ | 1832549336240619520 |
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| author | Andrea Actis Maximo Croci Emanuel Levin Rosa Bergoc |
| author_facet | Andrea Actis Maximo Croci Emanuel Levin Rosa Bergoc |
| author_sort | Andrea Actis |
| collection | DOAJ |
| description | Histopathological effects of cAMP analog (8-Chloro-cAMP), tamoxifen, and medroxyprogesterone, alone or combined, upon BALB/c mice uteri are reported. 8-Chloro-cAMP diminished uterine weight, but did not modify its histopathology or estral cycle significantly. Tamoxifen diminished uterine weight showing cystic hyperplasia and an estral cycle arrested at diestrus. Medroxyprogesterone increased uterine weight, caused a swelling of the endometrium and a pseudopregnancy estrus. When combined with 8-Chloro-cAMP, tamoxifen or medroxyprogesterone always had a predominant effect. We concluded that the effects of 8-Chloro-cAMP on mice uteri did not cause significant changes on its histopathology, but diminished its weight. |
| format | Article |
| id | doaj-art-db23725ff0534a12a0cb24e7fc63cc4a |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2002-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-db23725ff0534a12a0cb24e7fc63cc4a2025-02-03T06:11:31ZengWileyThe Scientific World Journal1537-744X2002-01-0121426143210.1100/tsw.2002.2828-Chloro-cAMP-Related Changes on Mice UteriAndrea Actis0Maximo Croci1Emanuel Levin2Rosa Bergoc3Department of Human Biochemistry, School of Medicine, University of Buenos Aires, Buenos Aires, ArgentinaInstitute of Immunooncology Dr. J.V. Crescenti, Buenos Aires, ArgentinaDepartment of Human Biochemistry, School of Medicine, University of Buenos Aires, Buenos Aires, ArgentinaRadioisotopes Laboratory, School of Pharmacy and Biochemistry, University of Buenos Aires, Junin St. 956 (1113), Buenos Aires, ArgentinaHistopathological effects of cAMP analog (8-Chloro-cAMP), tamoxifen, and medroxyprogesterone, alone or combined, upon BALB/c mice uteri are reported. 8-Chloro-cAMP diminished uterine weight, but did not modify its histopathology or estral cycle significantly. Tamoxifen diminished uterine weight showing cystic hyperplasia and an estral cycle arrested at diestrus. Medroxyprogesterone increased uterine weight, caused a swelling of the endometrium and a pseudopregnancy estrus. When combined with 8-Chloro-cAMP, tamoxifen or medroxyprogesterone always had a predominant effect. We concluded that the effects of 8-Chloro-cAMP on mice uteri did not cause significant changes on its histopathology, but diminished its weight.http://dx.doi.org/10.1100/tsw.2002.282 |
| spellingShingle | Andrea Actis Maximo Croci Emanuel Levin Rosa Bergoc 8-Chloro-cAMP-Related Changes on Mice Uteri The Scientific World Journal |
| title | 8-Chloro-cAMP-Related Changes on Mice Uteri |
| title_full | 8-Chloro-cAMP-Related Changes on Mice Uteri |
| title_fullStr | 8-Chloro-cAMP-Related Changes on Mice Uteri |
| title_full_unstemmed | 8-Chloro-cAMP-Related Changes on Mice Uteri |
| title_short | 8-Chloro-cAMP-Related Changes on Mice Uteri |
| title_sort | 8 chloro camp related changes on mice uteri |
| url | http://dx.doi.org/10.1100/tsw.2002.282 |
| work_keys_str_mv | AT andreaactis 8chlorocamprelatedchangesonmiceuteri AT maximocroci 8chlorocamprelatedchangesonmiceuteri AT emanuellevin 8chlorocamprelatedchangesonmiceuteri AT rosabergoc 8chlorocamprelatedchangesonmiceuteri |