Tumor-derived immunoglobulin-like transcript 3 inhibition reshapes the immunosuppressive tumor microenvironment and potentiates programmed cell death ligand 1 blockade immunotherapy in lung adenocarcinoma

Tumor-derived immunoglobulin-like transcript 3 inhibition reshapes the immunosuppressive tumor microenvironment and potentiates programmed cell death ligand 1 blockade immunotherapy in lung adenocarcinoma

The low response rate of current immune checkpoint inhibitors in cancer has necessitated the development of new immune targets.Survival and public databases analyses were performed to determine the clinical significance of immunoglobulin-like transcript 3 (ILT3). The impact of ILT3 and apolipoprotei...

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Bibliographic Details
Main Authors: Leirong Wang, Qing Li, Yanxin Sun, Shuyun Wang, Xuebing Fu, Xiufen Wang, Yan Zheng, Aiqin Gao, Yuping Sun, Juan Li
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Translational Oncology
Subjects:
Immunoglobulin-like transcript 3
Lung adenocarcinoma
Tumor-associated macrophage
T cell
Immunotherapy
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523325001123
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