Leprosy neuropathy: clinical presentations
Leprosy is a chronic infectious peripheral neuropathy caused by Mycobacterium leprae. The different clinical presentations of the disease are determined by the quality of the host immune response. Early detection of leprosy and treatment by multidrug therapy are the most important steps in preventin...
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| Format: | Article |
| Language: | English |
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Thieme Revinter Publicações
2013-09-01
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| Series: | Arquivos de Neuro-Psiquiatria |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013001000661&lng=en&tlng=en |
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| author | Osvaldo J M Nascimento |
| author_facet | Osvaldo J M Nascimento |
| author_sort | Osvaldo J M Nascimento |
| collection | DOAJ |
| description | Leprosy is a chronic infectious peripheral neuropathy caused by Mycobacterium leprae. The different clinical presentations of the disease are determined by the quality of the host immune response. Early detection of leprosy and treatment by multidrug therapy are the most important steps in preventing deformity and disability. Thus the early recognition of the clinical leprosy presentation is essential. Mononeuritis, mononeuritis multiplex (MM), polyneuritis (MM summation) are the most frequent. The frequent anesthetic skin lesions are absent in the pure neuritic leprosy presentation form. Isolated peripheral nerve involvement is common, including the cranial ones. Arthritic presentation is occasionally seen, usually misdiagnosed as rheumatoid arthritis. Attention should be given to autonomic dysfunctions in leprosy. There are clinical presentations with severe neuropathic pain - painful small-fiber neuropathy. Leprous late-onset neuropathy (LLON) clinical presentation should be considered facing a patient who develop an inflammatory neuropathy many years after a previous skin leprosy treatment. |
| format | Article |
| id | doaj-art-db1d718bfeeb45c5bab6ce7026634d66 |
| institution | DOAJ |
| issn | 1678-4227 |
| language | English |
| publishDate | 2013-09-01 |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-db1d718bfeeb45c5bab6ce7026634d662025-08-20T03:06:05ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42272013-09-01719B66166610.1590/0004-282X20130146S0004-282X2013001000661Leprosy neuropathy: clinical presentationsOsvaldo J M NascimentoLeprosy is a chronic infectious peripheral neuropathy caused by Mycobacterium leprae. The different clinical presentations of the disease are determined by the quality of the host immune response. Early detection of leprosy and treatment by multidrug therapy are the most important steps in preventing deformity and disability. Thus the early recognition of the clinical leprosy presentation is essential. Mononeuritis, mononeuritis multiplex (MM), polyneuritis (MM summation) are the most frequent. The frequent anesthetic skin lesions are absent in the pure neuritic leprosy presentation form. Isolated peripheral nerve involvement is common, including the cranial ones. Arthritic presentation is occasionally seen, usually misdiagnosed as rheumatoid arthritis. Attention should be given to autonomic dysfunctions in leprosy. There are clinical presentations with severe neuropathic pain - painful small-fiber neuropathy. Leprous late-onset neuropathy (LLON) clinical presentation should be considered facing a patient who develop an inflammatory neuropathy many years after a previous skin leprosy treatment.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013001000661&lng=en&tlng=enleprosy neuropathyclinical presentationspure neuritic formneuropathic painleprosy late-onset neuropathyarthritic leprosyautonomic leprosyreviewneuropatia da lepraapresentacoes clinicasforma neural purador neuropaticaneuropatia de inicio tardiolepra artriticaneuropatia autonomicarevisao |
| spellingShingle | Osvaldo J M Nascimento Leprosy neuropathy: clinical presentations Arquivos de Neuro-Psiquiatria leprosy neuropathy clinical presentations pure neuritic form neuropathic pain leprosy late-onset neuropathy arthritic leprosy autonomic leprosy review neuropatia da lepra apresentacoes clinicas forma neural pura dor neuropatica neuropatia de inicio tardio lepra artritica neuropatia autonomica revisao |
| title | Leprosy neuropathy: clinical presentations |
| title_full | Leprosy neuropathy: clinical presentations |
| title_fullStr | Leprosy neuropathy: clinical presentations |
| title_full_unstemmed | Leprosy neuropathy: clinical presentations |
| title_short | Leprosy neuropathy: clinical presentations |
| title_sort | leprosy neuropathy clinical presentations |
| topic | leprosy neuropathy clinical presentations pure neuritic form neuropathic pain leprosy late-onset neuropathy arthritic leprosy autonomic leprosy review neuropatia da lepra apresentacoes clinicas forma neural pura dor neuropatica neuropatia de inicio tardio lepra artritica neuropatia autonomica revisao |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013001000661&lng=en&tlng=en |
| work_keys_str_mv | AT osvaldojmnascimento leprosyneuropathyclinicalpresentations |