Self-assembled hybrid hydrogel microspheres create a bone marrow-mimicking niche for bone regeneration

Self-assembled hybrid hydrogel microspheres create a bone marrow-mimicking niche for bone regeneration

Bone marrow (BM), a natural niche rich in growth factors and bone marrow mesenchymal stem cells (BMSCs), provides an optimal regenerative microenvironment and is widely used in clinical applications. However, the limited proliferative capacity of BMSCs and the mismatch between bone regeneration and...

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Bibliographic Details
Main Authors: Zhi He, Peilun Hu, Zifan Li, Kaige Mao, Jingchuan Zheng, Chun-Yi Yang, Yuyang Luo, Jia Yang, Zheng Cao, Jingsong Lu, Xiaobin Luo, Sengpav Tong, Zhijun He, Kunkoo Kim, Yaosai Liu, Xiaodan Sun, Lingyun Zhao, Yongwei Pan, Yongping Cao, Yu Wang, Xiumei Wang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-12-01
Series:Bioactive Materials
Subjects:
Bone marrow
Bone marrow mesenchymal stem cells
Hydrogel microspheres
Bioactive peptides
Bone regeneration
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X25003561
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