Anti-tumour activity of zinc ionophore pyrithione in human ovarian cancer cells through inhibition of proliferation and migration and promotion of lysosome-mitochondrial apoptosis
Zinc pyrithione (ZPT) is widely used as an antimicrobial. Zinc is a necessary trace element of the human whose homeostasis associated with several cancers. However, the anticancer effect of increased Zinc in ovarian cancer is still unclear. This study focussed on the anti-tumour effects of ZPT combi...
Saved in:
| Main Authors: | Mengge Chen, Yanpeng Ding, Yuan Ke, Yifei Zeng, Nuomin Liu, Yahua Zhong, Xinying Hua, Zheng Li, Yudi Xiong, Chaoyan Wu, Haijun Yu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2020-01-01
|
| Series: | Artificial Cells, Nanomedicine, and Biotechnology |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/21691401.2020.1770266 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Zinc pyrithione is a potent inhibitor of PLPro and cathepsin L enzymes with ex vivo inhibition of SARS-CoV-2 entry and replication
by: Jerneja Kladnik, et al.
Published: (2022-12-01) -
Lanthanide conjugate Pr-MPO elicits anti-cancer activity by targeting lysosomal machinery and inducing zinc-dependent cataplerosis
by: Gregory Lucien Bellot, et al.
Published: (2024-10-01) -
South Ural state medical University, Department of Dermatovenerology
by: O. I. Letyaeva
Published: (2020-09-01) -
Characterization of the bioaccumulation and toxicity of copper pyrithione, an antifouling compound, on juveniles of rainbow trout
by: Bourdon, Charlotte, et al.
Published: (2024-01-01) -
The rapidly evolving view of lysosomal storage diseases
by: Giancarlo Parenti, et al.
Published: (2021-01-01)