Paracentral Acute Middle Maculopathy and Nonischemic Central Retinal Vein Obstruction in a Young Patient with Protein C Deficiency

Purpose. To report a case of protein C deficiency with paracentral acute middle maculopathy (PAMM) and nonischemic central retinal vein obstruction (NI-CRVO). Case Report. A previously healthy twenty-one-year-old male was referred with sudden-onset, painless, unilateral paracentral scotomata in the...

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Main Authors: Mojtaba Abrishami, Seyedeh Maryam Hosseini, Nasser Shoeibi, Hamid Reza Heidarzadeh
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Case Reports in Ophthalmological Medicine
Online Access:http://dx.doi.org/10.1155/2022/1237148
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author Mojtaba Abrishami
Seyedeh Maryam Hosseini
Nasser Shoeibi
Hamid Reza Heidarzadeh
author_facet Mojtaba Abrishami
Seyedeh Maryam Hosseini
Nasser Shoeibi
Hamid Reza Heidarzadeh
author_sort Mojtaba Abrishami
collection DOAJ
description Purpose. To report a case of protein C deficiency with paracentral acute middle maculopathy (PAMM) and nonischemic central retinal vein obstruction (NI-CRVO). Case Report. A previously healthy twenty-one-year-old male was referred with sudden-onset, painless, unilateral paracentral scotomata in the right eye for a week. His uncorrected visual acuity was 20/20 in both eyes. In fundus examination of the right eye, mild venous tortuosity, retinal hemorrhages, and a gray-white opacity in the papillomacular bundle were observed. In the macular spectral-domain optical coherence tomography images, a hyperreflective band was noticed at the level of the inner nuclear layer, indicating PAMM. Fundus appearance and fluorescein angiography findings indicated NI-CRVO diagnosis made. The systemic and laboratory evaluations disclosed a protein C deficiency. Conclusion. In this report, in a healthy young male, combined PAMM and NI-CRVO showed to be the cause of blurred vision in the setting of protein C deficiency.
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spelling doaj-art-db068868de9e48a6be2cea2d0d2c0b6f2025-08-20T02:21:25ZengWileyCase Reports in Ophthalmological Medicine2090-67302022-01-01202210.1155/2022/1237148Paracentral Acute Middle Maculopathy and Nonischemic Central Retinal Vein Obstruction in a Young Patient with Protein C DeficiencyMojtaba Abrishami0Seyedeh Maryam Hosseini1Nasser Shoeibi2Hamid Reza Heidarzadeh3Eye Research CenterEye Research CenterEye Research CenterEye Research CenterPurpose. To report a case of protein C deficiency with paracentral acute middle maculopathy (PAMM) and nonischemic central retinal vein obstruction (NI-CRVO). Case Report. A previously healthy twenty-one-year-old male was referred with sudden-onset, painless, unilateral paracentral scotomata in the right eye for a week. His uncorrected visual acuity was 20/20 in both eyes. In fundus examination of the right eye, mild venous tortuosity, retinal hemorrhages, and a gray-white opacity in the papillomacular bundle were observed. In the macular spectral-domain optical coherence tomography images, a hyperreflective band was noticed at the level of the inner nuclear layer, indicating PAMM. Fundus appearance and fluorescein angiography findings indicated NI-CRVO diagnosis made. The systemic and laboratory evaluations disclosed a protein C deficiency. Conclusion. In this report, in a healthy young male, combined PAMM and NI-CRVO showed to be the cause of blurred vision in the setting of protein C deficiency.http://dx.doi.org/10.1155/2022/1237148
spellingShingle Mojtaba Abrishami
Seyedeh Maryam Hosseini
Nasser Shoeibi
Hamid Reza Heidarzadeh
Paracentral Acute Middle Maculopathy and Nonischemic Central Retinal Vein Obstruction in a Young Patient with Protein C Deficiency
Case Reports in Ophthalmological Medicine
title Paracentral Acute Middle Maculopathy and Nonischemic Central Retinal Vein Obstruction in a Young Patient with Protein C Deficiency
title_full Paracentral Acute Middle Maculopathy and Nonischemic Central Retinal Vein Obstruction in a Young Patient with Protein C Deficiency
title_fullStr Paracentral Acute Middle Maculopathy and Nonischemic Central Retinal Vein Obstruction in a Young Patient with Protein C Deficiency
title_full_unstemmed Paracentral Acute Middle Maculopathy and Nonischemic Central Retinal Vein Obstruction in a Young Patient with Protein C Deficiency
title_short Paracentral Acute Middle Maculopathy and Nonischemic Central Retinal Vein Obstruction in a Young Patient with Protein C Deficiency
title_sort paracentral acute middle maculopathy and nonischemic central retinal vein obstruction in a young patient with protein c deficiency
url http://dx.doi.org/10.1155/2022/1237148
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