Vascular remodeling and TSLP/angiogenin overexpression in severe mixed asthma

Vascular remodeling and TSLP/angiogenin overexpression in severe mixed asthma

Abstract Background Asthma with neutrophilic/mixed inflammation is a difficult-to-control clinical phenotype. Currently, vascular and matrix airway remodeling in asthma with neutrophilic/mixed inflammation is not well known. We aimed to evaluate the differences in vascular/smooth muscle/matrix relat...

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Main Authors: Francesca Bertolini, Vitina M.A. Carriero, Elisa Arrigo, Giuseppe Guida, Stefano Levra, Stefano Pizzimenti, Mirella Profita, Isabella Gnemmi, Antonino Di Stefano, Fabio L.M. Ricciardolo
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Respiratory Research
Subjects:
Matrix-related remodeling
Vascular remodeling
Mixed/neutrophilic asthma
Severe asthma
Asthma exacerbation
Online Access:https://doi.org/10.1186/s12931-025-03133-9
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