Mortality and clinical outcomes of colistin versus colistin-based combination therapy for infections caused by Multidrug-resistant Acinetobacter baumannii in critically ill patients

Mortality and clinical outcomes of colistin versus colistin-based combination therapy for infections caused by Multidrug-resistant Acinetobacter baumannii in critically ill patients

Abstract Background Multidrug-resistant Acinetobacter baumannii emerged as a threatening “superbug” with significant morbidity and mortality and limited antimicrobial therapy options. The results of different antibiotic combination studies are heterogeneous and controversial. Further comparative stu...

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Main Authors: Marwan J. Alwazzeh, Jumanah Algazaq, Fatimah Ali Al-Salem, Fatimah Alabkari, Sara M. Alwarthan, Mashael Alhajri, Bashayer M. AlShehail, Amani Alnimr, Ahmad Wajeeh Alrefaai, Faten Hussain Alsaihati, Fahd Abdulaziz Almuhanna
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Infectious Diseases
Subjects:
Acinetobacter baumannii
Colistin
Carbapenem
Tigecycline
Combination
Outcome
Online Access:https://doi.org/10.1186/s12879-025-10781-1
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