Ferrocene Derivatives Carrying Urea, Thiourea, and Sulfonamide Moieties: Synthesis and Evaluation of Antibacterial and Antifungal Activities
In the present study, some novel ferrocene derivatives carrying urea, thiourea, and sulfonamide groups were synthesized, and all compounds were characterized by spectral and elemental analyses. These compounds were screened for their antibacterial activities and also their minimum inhibitory concent...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2013/149693 |
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| _version_ | 1849472718705000448 |
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| author | Serkan Yavuz Hilal Yıldırım |
| author_facet | Serkan Yavuz Hilal Yıldırım |
| author_sort | Serkan Yavuz |
| collection | DOAJ |
| description | In the present study, some novel ferrocene derivatives carrying urea, thiourea, and sulfonamide groups were synthesized, and all compounds were characterized by spectral and elemental analyses. These compounds were screened for their antibacterial activities and also their minimum inhibitory concentration (MIC) against Gram-positive bacteria (Staphylococcus aureus and Bacillus subtilis) and Gram-negative bacteria (Klebsiella pneumonia and Escherichia coli) and antifungal activities against Saccharomyces cerevisiae and Candida albicans. Amongst the tested compounds, 4b, 4c, 5b, and 6b displayed excellent antimicrobial activity. |
| format | Article |
| id | doaj-art-db01132c5b2641278ecb5ae0168262c7 |
| institution | Kabale University |
| issn | 2090-9063 2090-9071 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Chemistry |
| spelling | doaj-art-db01132c5b2641278ecb5ae0168262c72025-08-20T03:24:26ZengWileyJournal of Chemistry2090-90632090-90712013-01-01201310.1155/2013/149693149693Ferrocene Derivatives Carrying Urea, Thiourea, and Sulfonamide Moieties: Synthesis and Evaluation of Antibacterial and Antifungal ActivitiesSerkan Yavuz0Hilal Yıldırım1Department of Chemistry, Faculty of Science, Gazi University, 06500 Ankara, TurkeyDepartment of Chemistry, Faculty of Science and Arts, Kırıkkale University, 71450 Kırıkkale, TurkeyIn the present study, some novel ferrocene derivatives carrying urea, thiourea, and sulfonamide groups were synthesized, and all compounds were characterized by spectral and elemental analyses. These compounds were screened for their antibacterial activities and also their minimum inhibitory concentration (MIC) against Gram-positive bacteria (Staphylococcus aureus and Bacillus subtilis) and Gram-negative bacteria (Klebsiella pneumonia and Escherichia coli) and antifungal activities against Saccharomyces cerevisiae and Candida albicans. Amongst the tested compounds, 4b, 4c, 5b, and 6b displayed excellent antimicrobial activity.http://dx.doi.org/10.1155/2013/149693 |
| spellingShingle | Serkan Yavuz Hilal Yıldırım Ferrocene Derivatives Carrying Urea, Thiourea, and Sulfonamide Moieties: Synthesis and Evaluation of Antibacterial and Antifungal Activities Journal of Chemistry |
| title | Ferrocene Derivatives Carrying Urea, Thiourea, and Sulfonamide Moieties: Synthesis and Evaluation of Antibacterial and Antifungal Activities |
| title_full | Ferrocene Derivatives Carrying Urea, Thiourea, and Sulfonamide Moieties: Synthesis and Evaluation of Antibacterial and Antifungal Activities |
| title_fullStr | Ferrocene Derivatives Carrying Urea, Thiourea, and Sulfonamide Moieties: Synthesis and Evaluation of Antibacterial and Antifungal Activities |
| title_full_unstemmed | Ferrocene Derivatives Carrying Urea, Thiourea, and Sulfonamide Moieties: Synthesis and Evaluation of Antibacterial and Antifungal Activities |
| title_short | Ferrocene Derivatives Carrying Urea, Thiourea, and Sulfonamide Moieties: Synthesis and Evaluation of Antibacterial and Antifungal Activities |
| title_sort | ferrocene derivatives carrying urea thiourea and sulfonamide moieties synthesis and evaluation of antibacterial and antifungal activities |
| url | http://dx.doi.org/10.1155/2013/149693 |
| work_keys_str_mv | AT serkanyavuz ferrocenederivativescarryingureathioureaandsulfonamidemoietiessynthesisandevaluationofantibacterialandantifungalactivities AT hilalyıldırım ferrocenederivativescarryingureathioureaandsulfonamidemoietiessynthesisandevaluationofantibacterialandantifungalactivities |