ciRS-7 expression is epigenetically regulated in cancer cells across human adenocarcinomas.

Circular RNAs (circRNAs) constitute a large class of non-coding RNAs with gene regulatory capabilities, mainly through microRNA binding, a mechanism that has been linked to cancer development. The circRNA ciRS-7 (also known as CDR1as) is an interesting candidate as it harbors over 60 binding sites f...

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Bibliographic Details
Main Authors: Thea P Paasch, Morten T Jarlstad Olesen, Juan L García-Rodríguez, Adrienne M Assmus, Robert A Fenton, Jørgen Kjems, Henrik Hager, Lasse S Kristensen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-06-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1011726
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