Nuclear Receptors: Mechanistic Insights into Endocrine Resistance in Prostate and Breast Cancers
This review focuses on the pivotal roles of nuclear receptors (NRs) in driving endocrine resistance in prostate and breast cancers. In prostate cancer (PCa), androgen receptor (AR) amplification, mutations, and altered coactivator interactions sustain tumor growth under androgen deprivation therapy...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-10-01
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| Series: | Receptors |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2813-2564/3/4/22 |
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