External Beam Radiotherapy for Bilateral Leukemic Infiltrative Optic Neuropathy in a Pediatric Patient
Objective: To describe a rare case of acute lymphocytic leukemia (ALL) with optic nerve head tumor cell infiltration treated with external beam irradiation. Methods: This is a case report. Results: A 13-year old female with ALL complaining of blurred vision was found to have leukemic optic ne...
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Philippine Academy of Ophthalmology
2022-06-01
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| Series: | Philippine Journal of Ophthalmology |
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| Online Access: | https://paojournal.com/index.php/pjo/article/view/67 |
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| author | Amapola M. Oropilla MD Junn Pajarillo MD, DPBO |
| author_facet | Amapola M. Oropilla MD Junn Pajarillo MD, DPBO |
| author_sort | Amapola M. Oropilla MD |
| collection | DOAJ |
| description | Objective: To describe a rare case of acute lymphocytic leukemia (ALL) with optic nerve head tumor cell infiltration treated with external beam irradiation.
Methods: This is a case report.
Results: A 13-year old female with ALL complaining of blurred vision was found to have leukemic optic nerve head infiltration as evidenced by the presence of bilateral large, poorly-circumscribed, white masses covering the optic discs. She underwent external beam radiotherapy with total dose of 3000cGy. Four months posttreatment, there was marked reduction in tumor bulk with corresponding partial but significant visual improvement. No post-radiation complications were noted.
Conclusion: External beam irradiation is an effective treatment in reducing tumor bulk secondary to leukemic infiltration of the optic nerve with no significant collateral damage to adjacent ocular and periocular tissue. Early intervention is warranted to maximize visual recovery |
| format | Article |
| id | doaj-art-daf10749ab91465c9d847c2c115a4792 |
| institution | OA Journals |
| issn | 0031-7659 |
| language | English |
| publishDate | 2022-06-01 |
| publisher | Philippine Academy of Ophthalmology |
| record_format | Article |
| series | Philippine Journal of Ophthalmology |
| spelling | doaj-art-daf10749ab91465c9d847c2c115a47922025-08-20T02:04:53ZengPhilippine Academy of OphthalmologyPhilippine Journal of Ophthalmology0031-76592022-06-01471404467External Beam Radiotherapy for Bilateral Leukemic Infiltrative Optic Neuropathy in a Pediatric PatientAmapola M. Oropilla MD0Junn Pajarillo MD, DPBO1Department of Ophthalmology. Ilocos Training and Regional Medical Center, San Fernando City, La UnionDepartment of Ophthalmology. Ilocos Training and Regional Medical Center, San Fernando City, La UnionObjective: To describe a rare case of acute lymphocytic leukemia (ALL) with optic nerve head tumor cell infiltration treated with external beam irradiation. Methods: This is a case report. Results: A 13-year old female with ALL complaining of blurred vision was found to have leukemic optic nerve head infiltration as evidenced by the presence of bilateral large, poorly-circumscribed, white masses covering the optic discs. She underwent external beam radiotherapy with total dose of 3000cGy. Four months posttreatment, there was marked reduction in tumor bulk with corresponding partial but significant visual improvement. No post-radiation complications were noted. Conclusion: External beam irradiation is an effective treatment in reducing tumor bulk secondary to leukemic infiltration of the optic nerve with no significant collateral damage to adjacent ocular and periocular tissue. Early intervention is warranted to maximize visual recoveryhttps://paojournal.com/index.php/pjo/article/view/67acute lymphocytic leukemiaoptic nervepediatricradiotherapy |
| spellingShingle | Amapola M. Oropilla MD Junn Pajarillo MD, DPBO External Beam Radiotherapy for Bilateral Leukemic Infiltrative Optic Neuropathy in a Pediatric Patient Philippine Journal of Ophthalmology acute lymphocytic leukemia optic nerve pediatric radiotherapy |
| title | External Beam Radiotherapy for Bilateral Leukemic Infiltrative Optic Neuropathy in a Pediatric Patient |
| title_full | External Beam Radiotherapy for Bilateral Leukemic Infiltrative Optic Neuropathy in a Pediatric Patient |
| title_fullStr | External Beam Radiotherapy for Bilateral Leukemic Infiltrative Optic Neuropathy in a Pediatric Patient |
| title_full_unstemmed | External Beam Radiotherapy for Bilateral Leukemic Infiltrative Optic Neuropathy in a Pediatric Patient |
| title_short | External Beam Radiotherapy for Bilateral Leukemic Infiltrative Optic Neuropathy in a Pediatric Patient |
| title_sort | external beam radiotherapy for bilateral leukemic infiltrative optic neuropathy in a pediatric patient |
| topic | acute lymphocytic leukemia optic nerve pediatric radiotherapy |
| url | https://paojournal.com/index.php/pjo/article/view/67 |
| work_keys_str_mv | AT amapolamoropillamd externalbeamradiotherapyforbilateralleukemicinfiltrativeopticneuropathyinapediatricpatient AT junnpajarillomddpbo externalbeamradiotherapyforbilateralleukemicinfiltrativeopticneuropathyinapediatricpatient |