Limited utility of subendometrial enhancement in assessing the interface between the endometrium and myometrium

Abstract This study was conducted to re-evaluate the utility of subendometrial enhancement (SEE) in assessing the interface between the endometrium and myometrium. In total, 110 women who underwent pelvic magnetic resonance imaging (MRI) for non-endometrial gynecologic diseases were enrolled in this...

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Main Authors: Sang Youn Kim, Myoung Seok Lee, Min Hoan Moon, Chang Kyu Sung, Sohee Oh
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-024-74752-3
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author Sang Youn Kim
Myoung Seok Lee
Min Hoan Moon
Chang Kyu Sung
Sohee Oh
author_facet Sang Youn Kim
Myoung Seok Lee
Min Hoan Moon
Chang Kyu Sung
Sohee Oh
author_sort Sang Youn Kim
collection DOAJ
description Abstract This study was conducted to re-evaluate the utility of subendometrial enhancement (SEE) in assessing the interface between the endometrium and myometrium. In total, 110 women who underwent pelvic magnetic resonance imaging (MRI) for non-endometrial gynecologic diseases were enrolled in this prospective study. Two radiologists independently assessed the presence or absence of subendometrial enhancement (SEE) on dynamic contrast-enhanced (CE) MRI. A subgroup analysis was performed to evaluate the impact of menstrual status on the detection of SEE. Identified areas of SEE were rated using a 4-point Likert scale to determine their reliability in assessing the interface between the endometrium and myometrium. SEE was identified in 44.5% (49/110) of cases by radiologist 1 and in 39.1% (43/110) by radiologist 2. A subgroup analysis indicated no significant differences in the detection of SEE based on menstrual status. The identified areas of SEE were deemed reliable for assessing the interface between the endometrium and myometrium in 24.5% (12/49) of the cases evaluated by radiologist 1 and in 32.6% (14/43) of those evaluated by radiologist 2. Among the 110 women studied, reliable areas of SEE for assessing the interface between the endometrium and myometrium were observed in 10.9% (n = 12) by radiologist 1 and 12.7% (n = 14) by radiologist 2. The evaluation of SEE using dynamic CE MRI may be limited in its ability to assess the interface between the endometrium and myometrium.
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spelling doaj-art-daee8ad851d344ce867c8d63048dfff42025-08-20T02:17:47ZengNature PortfolioScientific Reports2045-23222024-10-011411710.1038/s41598-024-74752-3Limited utility of subendometrial enhancement in assessing the interface between the endometrium and myometriumSang Youn Kim0Myoung Seok Lee1Min Hoan Moon2Chang Kyu Sung3Sohee Oh4Department of Radiology, Seoul National University Hospital, Seoul National University College of MedicineDepartment of Radiology, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul National University College of MedicineDepartment of Radiology, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul National University College of MedicineDepartment of Radiology, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul National University College of MedicineMedical Research Collaborating Center, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul National University College of MedicineAbstract This study was conducted to re-evaluate the utility of subendometrial enhancement (SEE) in assessing the interface between the endometrium and myometrium. In total, 110 women who underwent pelvic magnetic resonance imaging (MRI) for non-endometrial gynecologic diseases were enrolled in this prospective study. Two radiologists independently assessed the presence or absence of subendometrial enhancement (SEE) on dynamic contrast-enhanced (CE) MRI. A subgroup analysis was performed to evaluate the impact of menstrual status on the detection of SEE. Identified areas of SEE were rated using a 4-point Likert scale to determine their reliability in assessing the interface between the endometrium and myometrium. SEE was identified in 44.5% (49/110) of cases by radiologist 1 and in 39.1% (43/110) by radiologist 2. A subgroup analysis indicated no significant differences in the detection of SEE based on menstrual status. The identified areas of SEE were deemed reliable for assessing the interface between the endometrium and myometrium in 24.5% (12/49) of the cases evaluated by radiologist 1 and in 32.6% (14/43) of those evaluated by radiologist 2. Among the 110 women studied, reliable areas of SEE for assessing the interface between the endometrium and myometrium were observed in 10.9% (n = 12) by radiologist 1 and 12.7% (n = 14) by radiologist 2. The evaluation of SEE using dynamic CE MRI may be limited in its ability to assess the interface between the endometrium and myometrium.https://doi.org/10.1038/s41598-024-74752-3Magnetic resonance imagingContrast mediaFemale genitaliaUterusEndometrial neoplasm
spellingShingle Sang Youn Kim
Myoung Seok Lee
Min Hoan Moon
Chang Kyu Sung
Sohee Oh
Limited utility of subendometrial enhancement in assessing the interface between the endometrium and myometrium
Scientific Reports
Magnetic resonance imaging
Contrast media
Female genitalia
Uterus
Endometrial neoplasm
title Limited utility of subendometrial enhancement in assessing the interface between the endometrium and myometrium
title_full Limited utility of subendometrial enhancement in assessing the interface between the endometrium and myometrium
title_fullStr Limited utility of subendometrial enhancement in assessing the interface between the endometrium and myometrium
title_full_unstemmed Limited utility of subendometrial enhancement in assessing the interface between the endometrium and myometrium
title_short Limited utility of subendometrial enhancement in assessing the interface between the endometrium and myometrium
title_sort limited utility of subendometrial enhancement in assessing the interface between the endometrium and myometrium
topic Magnetic resonance imaging
Contrast media
Female genitalia
Uterus
Endometrial neoplasm
url https://doi.org/10.1038/s41598-024-74752-3
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