Anti-oxidant and anti-bacterial effects of Diospyros kaki leaf extract in Vietnam
Diospyros kaki is a famous commercial plant with its edible fruit (persimmon) and is widely used as a traditional remedy in Vietnam. However, the anti-oxidant and anti-bacterial effects against gastrointestinal microbes of the D. kaki leaf extract have not been elucidated yet. In this study, the met...
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HO CHI MINH CITY OPEN UNIVERSITY JOURNAL OF SCIENCE
2025-01-01
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| Series: | Ho Chi Minh City Open University Journal of Science - Engineering and Technology |
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| Online Access: | https://journalofscience.ou.edu.vn/index.php/tech-en/article/view/3502 |
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| author | Thao Thi Xuan Tran Ty Viet Pham Luong Tuan Lam Binh Tinh Hua Ngoc Bich Nguyen Bich Hang Do Buu Gia Tran |
| author_facet | Thao Thi Xuan Tran Ty Viet Pham Luong Tuan Lam Binh Tinh Hua Ngoc Bich Nguyen Bich Hang Do Buu Gia Tran |
| author_sort | Thao Thi Xuan Tran |
| collection | DOAJ |
| description | Diospyros kaki is a famous commercial plant with its edible fruit (persimmon) and is widely used as a traditional remedy in Vietnam. However, the anti-oxidant and anti-bacterial effects against gastrointestinal microbes of the D. kaki leaf extract have not been elucidated yet. In this study, the methanol extract from
D. kaki leaves contained some chemical groups, such as tannins, flavonoids, phenolic compounds, alkaloids, and saponins, mainly it was rich in polyphenols and flavonoids (528.11 ± 12.96 mg GAE/g and 44.49 ± 6.77 mg QE/g, respectively). The extract exhibited a strong anti-oxidant ability (DPPH scavenging activity of about 91.83 ± 1.02% and total anti-oxidant capacity of approximately 110.58 ± 2.65 mg AAE/g). Furthermore, the anti-bacterial activity of the extract against some gastrointestinal bacteria, including Staphylococcus aureus, Enterococcus durans, Enterococcus faecium, and Yersinia enterocolitica, has been reported for the first time (the zone of inhibition ranging from 14.17 - 24.67mm).
MIC of the extract was 0.6125 - 1.25 mg/mL, and MBC was
2.5 - 5 mg/mL, which implied the extract exerted a bactericidal effect. These findings suggest D. kaki leaf extract is a promising source of extracting bioactive compounds, such as anti-oxidant and anti-microbial agents, and a potential medicine for the treatment of gastrointestinal infections. |
| format | Article |
| id | doaj-art-daee13dc14304262a9ce6e906d59ac88 |
| institution | OA Journals |
| issn | 2734-9330 2734-9608 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | HO CHI MINH CITY OPEN UNIVERSITY JOURNAL OF SCIENCE |
| record_format | Article |
| series | Ho Chi Minh City Open University Journal of Science - Engineering and Technology |
| spelling | doaj-art-daee13dc14304262a9ce6e906d59ac882025-08-20T02:27:15ZengHO CHI MINH CITY OPEN UNIVERSITY JOURNAL OF SCIENCEHo Chi Minh City Open University Journal of Science - Engineering and Technology2734-93302734-96082025-01-01151152710.46223/HCMCOUJS.tech.en.15.1.3502.20252361Anti-oxidant and anti-bacterial effects of Diospyros kaki leaf extract in VietnamThao Thi Xuan Tran0Ty Viet Pham1Luong Tuan Lam2Binh Tinh Hua3Ngoc Bich Nguyen4Bich Hang Do5Buu Gia Tran6Ton Duc Thang University, Ho Chi Minh CityUniversity of Education, Hue University, Hue CityTon Duc Thang University, Ho Chi Minh CityTon Duc Thang University, Ho Chi Minh CityTon Duc Thang University, Ho Chi Minh CityTon Duc Thang University, Ho Chi Minh CityTon Duc Thang University, Ho Chi Minh CityDiospyros kaki is a famous commercial plant with its edible fruit (persimmon) and is widely used as a traditional remedy in Vietnam. However, the anti-oxidant and anti-bacterial effects against gastrointestinal microbes of the D. kaki leaf extract have not been elucidated yet. In this study, the methanol extract from D. kaki leaves contained some chemical groups, such as tannins, flavonoids, phenolic compounds, alkaloids, and saponins, mainly it was rich in polyphenols and flavonoids (528.11 ± 12.96 mg GAE/g and 44.49 ± 6.77 mg QE/g, respectively). The extract exhibited a strong anti-oxidant ability (DPPH scavenging activity of about 91.83 ± 1.02% and total anti-oxidant capacity of approximately 110.58 ± 2.65 mg AAE/g). Furthermore, the anti-bacterial activity of the extract against some gastrointestinal bacteria, including Staphylococcus aureus, Enterococcus durans, Enterococcus faecium, and Yersinia enterocolitica, has been reported for the first time (the zone of inhibition ranging from 14.17 - 24.67mm). MIC of the extract was 0.6125 - 1.25 mg/mL, and MBC was 2.5 - 5 mg/mL, which implied the extract exerted a bactericidal effect. These findings suggest D. kaki leaf extract is a promising source of extracting bioactive compounds, such as anti-oxidant and anti-microbial agents, and a potential medicine for the treatment of gastrointestinal infections.https://journalofscience.ou.edu.vn/index.php/tech-en/article/view/3502anti-bacterial effectanti-oxidant activitydiospyros kakiethno-pharmacologygastrointestinal bacteria |
| spellingShingle | Thao Thi Xuan Tran Ty Viet Pham Luong Tuan Lam Binh Tinh Hua Ngoc Bich Nguyen Bich Hang Do Buu Gia Tran Anti-oxidant and anti-bacterial effects of Diospyros kaki leaf extract in Vietnam Ho Chi Minh City Open University Journal of Science - Engineering and Technology anti-bacterial effect anti-oxidant activity diospyros kaki ethno-pharmacology gastrointestinal bacteria |
| title | Anti-oxidant and anti-bacterial effects of Diospyros kaki leaf extract in Vietnam |
| title_full | Anti-oxidant and anti-bacterial effects of Diospyros kaki leaf extract in Vietnam |
| title_fullStr | Anti-oxidant and anti-bacterial effects of Diospyros kaki leaf extract in Vietnam |
| title_full_unstemmed | Anti-oxidant and anti-bacterial effects of Diospyros kaki leaf extract in Vietnam |
| title_short | Anti-oxidant and anti-bacterial effects of Diospyros kaki leaf extract in Vietnam |
| title_sort | anti oxidant and anti bacterial effects of diospyros kaki leaf extract in vietnam |
| topic | anti-bacterial effect anti-oxidant activity diospyros kaki ethno-pharmacology gastrointestinal bacteria |
| url | https://journalofscience.ou.edu.vn/index.php/tech-en/article/view/3502 |
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