Assessment of maternal health and behavior during pregnancy in the HEALthy Brain and Child Development Study: Rationale and approach

The Healthy Brain and Child Development (HBCD) Study, a multi-site, prospective, longitudinal cohort study, will examine human brain, cognitive, behavioral, social, and emotional development beginning prenatally and planned through early childhood. Prenatal exposures, including substances of abuse,...

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Main Authors: Kelly K. Gurka, Heather H. Burris, Lucia Ciciolla, Claire D. Coles, Suena H. Massey, Sharlene Newman, Vidya Rajagopalan, Lynne M. Smith, Anna Zilverstand, Gretchen Bandoli
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Developmental Cognitive Neuroscience
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Online Access:http://www.sciencedirect.com/science/article/pii/S1878929324001555
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author Kelly K. Gurka
Heather H. Burris
Lucia Ciciolla
Claire D. Coles
Suena H. Massey
Sharlene Newman
Vidya Rajagopalan
Lynne M. Smith
Anna Zilverstand
Gretchen Bandoli
author_facet Kelly K. Gurka
Heather H. Burris
Lucia Ciciolla
Claire D. Coles
Suena H. Massey
Sharlene Newman
Vidya Rajagopalan
Lynne M. Smith
Anna Zilverstand
Gretchen Bandoli
author_sort Kelly K. Gurka
collection DOAJ
description The Healthy Brain and Child Development (HBCD) Study, a multi-site, prospective, longitudinal cohort study, will examine human brain, cognitive, behavioral, social, and emotional development beginning prenatally and planned through early childhood. Prenatal exposures, including substances of abuse, impact fetal development and have effects across the life course. During the development of the HBCD Study, the Pregnancy Exposures, Including Substances Workgroup (WG-PRG) was charged with characterizing maternal health and behavior during pregnancy into the childhood years. Maternal physical and mental health, including substance use, and pregnancy and birth complications and outcomes were prioritized. Pregnancy, chronic and acute health conditions, family mental health, and healthcare utilization were assessed using existing and novel measures. Maternal mental health was assessed with the Edinburgh Postpartum Depression Scale, select items in the DSM-5 Self-Rated Level-1 and −2 Cross-Cutting Symptom Measures, and the National Stressful Events Survey-PTSD Short Scale. Finally, participants reported lifetime, recent, and current use of substances using a modified-ASSIST during pregnancy and postpartum. Quantities and frequencies of reported substances were collected for select periods prior to and during pregnancy through an interview (or web application) using the timeline-followback method. HBCD will advance our understanding of the impact of the intrauterine environment on early development.
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spelling doaj-art-daeb3ef8949644929009f9fe81438c352025-01-22T05:41:18ZengElsevierDevelopmental Cognitive Neuroscience1878-92932025-01-0171101494Assessment of maternal health and behavior during pregnancy in the HEALthy Brain and Child Development Study: Rationale and approachKelly K. Gurka0Heather H. Burris1Lucia Ciciolla2Claire D. Coles3Suena H. Massey4Sharlene Newman5Vidya Rajagopalan6Lynne M. Smith7Anna Zilverstand8Gretchen Bandoli9University of Florida, PO Box 100231, Gainesville, FL 32610-0231, USA; Correspondence to: University of Virginia, PO Box 800828, Charlottesville, VA 22908-0828, USA.Children’s Hospital of Philadelphia, University of Pennsylvania, 734 Schuylkill Ave, Room 19363, Philadelphia, PA 19146, USAOklahoma State University, 116 Psychology Building, Stillwater, OK 74074, USAEmory University School of Medicine, 12 Executive Park Drive, Atlanta, GA 30329, USAMassachusetts General Hosptial, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USAUniversity of Alabama, NE Medical Building, Box 870328, Tuscaloosa, AL 35487, USAChildren’s Hospital Los Angeles, Keck School of Medicine, University of Southern California, 4650 Sunset Blvd, Los Angeles, CA 90703, USAHarbor-UCLA Medical Center, 1124 West Carson Street, Box 17, Torrance, CA 90502, USAUniversity of Minnesota, 717 Delaware Street, Minneapolis, MN 55414, USAUniversity of California San Diego, 9500 Gilman Drive, MC 0828, La Jolla, CA 92093, USAThe Healthy Brain and Child Development (HBCD) Study, a multi-site, prospective, longitudinal cohort study, will examine human brain, cognitive, behavioral, social, and emotional development beginning prenatally and planned through early childhood. Prenatal exposures, including substances of abuse, impact fetal development and have effects across the life course. During the development of the HBCD Study, the Pregnancy Exposures, Including Substances Workgroup (WG-PRG) was charged with characterizing maternal health and behavior during pregnancy into the childhood years. Maternal physical and mental health, including substance use, and pregnancy and birth complications and outcomes were prioritized. Pregnancy, chronic and acute health conditions, family mental health, and healthcare utilization were assessed using existing and novel measures. Maternal mental health was assessed with the Edinburgh Postpartum Depression Scale, select items in the DSM-5 Self-Rated Level-1 and −2 Cross-Cutting Symptom Measures, and the National Stressful Events Survey-PTSD Short Scale. Finally, participants reported lifetime, recent, and current use of substances using a modified-ASSIST during pregnancy and postpartum. Quantities and frequencies of reported substances were collected for select periods prior to and during pregnancy through an interview (or web application) using the timeline-followback method. HBCD will advance our understanding of the impact of the intrauterine environment on early development.http://www.sciencedirect.com/science/article/pii/S1878929324001555BrainChild developmentHBCDMaternal healthPregnancyPrenatal exposure delayed effects
spellingShingle Kelly K. Gurka
Heather H. Burris
Lucia Ciciolla
Claire D. Coles
Suena H. Massey
Sharlene Newman
Vidya Rajagopalan
Lynne M. Smith
Anna Zilverstand
Gretchen Bandoli
Assessment of maternal health and behavior during pregnancy in the HEALthy Brain and Child Development Study: Rationale and approach
Developmental Cognitive Neuroscience
Brain
Child development
HBCD
Maternal health
Pregnancy
Prenatal exposure delayed effects
title Assessment of maternal health and behavior during pregnancy in the HEALthy Brain and Child Development Study: Rationale and approach
title_full Assessment of maternal health and behavior during pregnancy in the HEALthy Brain and Child Development Study: Rationale and approach
title_fullStr Assessment of maternal health and behavior during pregnancy in the HEALthy Brain and Child Development Study: Rationale and approach
title_full_unstemmed Assessment of maternal health and behavior during pregnancy in the HEALthy Brain and Child Development Study: Rationale and approach
title_short Assessment of maternal health and behavior during pregnancy in the HEALthy Brain and Child Development Study: Rationale and approach
title_sort assessment of maternal health and behavior during pregnancy in the healthy brain and child development study rationale and approach
topic Brain
Child development
HBCD
Maternal health
Pregnancy
Prenatal exposure delayed effects
url http://www.sciencedirect.com/science/article/pii/S1878929324001555
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