Investigation of parasite genetic variation and systemic immune responses in patients presenting with different clinical presentations of cutaneous leishmaniasis caused by Leishmania aethiopica

Investigation of parasite genetic variation and systemic immune responses in patients presenting with different clinical presentations of cutaneous leishmaniasis caused by Leishmania aethiopica

Abstract Background Cutaneous leishmaniasis (CL) is a neglected tropical skin disease, caused by the protozoan parasite Leishmania. In Ethiopia, CL is mainly caused by Leishmania aethiopica and can present in different clinical forms. The aim of this study was to assess whether these different forms...

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Main Authors: Endalew Yizengaw, Yegnasew Takele, Susanne Franssen, Bizuayehu Gashaw, Mulat Yimer, Emebet Adem, Endalkachew Nibret, Gizachew Yismaw, Edward Cruz Cervera, Kefale Ejigu, Dessalegn Tamiru, Abaineh Munshea, Ingrid Müller, Richard Weller, James A. Cotton, Pascale Kropf
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Infectious Diseases of Poverty
Subjects:
Cutaneous leishmaniasis
Leishmania aethiopica
Genetics
Cytokines
Chemokines
Plasma
Online Access:https://doi.org/10.1186/s40249-024-01244-x
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