FACTORS ASSOCIATED WITH THE DEVELOPMENT OF SECONDARY HYPERPARATHYROIDISM IN PATIENTS WITH TYPE 1 DIABETES MELLITUS WITH DIABETIC NEPHROPATHY
Objective. To identify factors associated with the development of secondary hyperparathyroidism in patients with type 1 diabetes mellitus with diabetic nephropathy.Materials and methods. One hundred and one patients (males) with type 1 diabetes mellitus with diabetic nephropathy who were treated in...
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Siberian State Medical University (Tomsk)
2014-04-01
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| Series: | Бюллетень сибирской медицины |
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| Online Access: | https://bulletin.ssmu.ru/jour/article/view/30 |
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| author | Ye. A. Khantakova |
| author_facet | Ye. A. Khantakova |
| author_sort | Ye. A. Khantakova |
| collection | DOAJ |
| description | Objective. To identify factors associated with the development of secondary hyperparathyroidism in patients with type 1 diabetes mellitus with diabetic nephropathy.Materials and methods. One hundred and one patients (males) with type 1 diabetes mellitus with diabetic nephropathy who were treated in endocrinology department of the Regional clinical hospital were examined. For the study of calcium and phosphorus metabolism in patients with type 1 diabetes mellitus, we investigated the following parameters in the blood plasma: level of intact parathyroid hormone, total calcium, ionized calcium, serum phosphorus.Results. The study showed that in patients with type 1 diabetes mellitus with diabetic nephropathy factors associated with the development of secondary hyperparathyroidism are: the age above 30 years old, the duration of diabetes for more than 15 years, reduction of glomerular filtration rate of less than70 ml/min/1,73 m2 and the development of anemia. Factor associated with the reduction of secondaryhyperparathyroidism is the level of glycated hemoglobin of more than 8%.Conclusion. Thus, patients with type 1 diabetes mellitus with diabetic nephropathy represent a group of increased risk for development of violations of calcium and phosphorus metabolism. Analysis of the factors associated with the occurrence of secondary hyperparathyroidism in diabetic nephropathy allowed to identify a group of high risk of development of this pathology. |
| format | Article |
| id | doaj-art-dae8dfcd21e349bb9dcc21faa614b9c3 |
| institution | DOAJ |
| issn | 1682-0363 1819-3684 |
| language | English |
| publishDate | 2014-04-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj-art-dae8dfcd21e349bb9dcc21faa614b9c32025-08-20T03:21:43ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842014-04-01132546010.20538/1682-0363-2014-2-54-6030FACTORS ASSOCIATED WITH THE DEVELOPMENT OF SECONDARY HYPERPARATHYROIDISM IN PATIENTS WITH TYPE 1 DIABETES MELLITUS WITH DIABETIC NEPHROPATHYYe. A. Khantakova0Irkutsk State Medical University, IrkutskObjective. To identify factors associated with the development of secondary hyperparathyroidism in patients with type 1 diabetes mellitus with diabetic nephropathy.Materials and methods. One hundred and one patients (males) with type 1 diabetes mellitus with diabetic nephropathy who were treated in endocrinology department of the Regional clinical hospital were examined. For the study of calcium and phosphorus metabolism in patients with type 1 diabetes mellitus, we investigated the following parameters in the blood plasma: level of intact parathyroid hormone, total calcium, ionized calcium, serum phosphorus.Results. The study showed that in patients with type 1 diabetes mellitus with diabetic nephropathy factors associated with the development of secondary hyperparathyroidism are: the age above 30 years old, the duration of diabetes for more than 15 years, reduction of glomerular filtration rate of less than70 ml/min/1,73 m2 and the development of anemia. Factor associated with the reduction of secondaryhyperparathyroidism is the level of glycated hemoglobin of more than 8%.Conclusion. Thus, patients with type 1 diabetes mellitus with diabetic nephropathy represent a group of increased risk for development of violations of calcium and phosphorus metabolism. Analysis of the factors associated with the occurrence of secondary hyperparathyroidism in diabetic nephropathy allowed to identify a group of high risk of development of this pathology.https://bulletin.ssmu.ru/jour/article/view/30type 1 diabetes mellitusdiabetic nephropathysecondary hyperparathyroidism |
| spellingShingle | Ye. A. Khantakova FACTORS ASSOCIATED WITH THE DEVELOPMENT OF SECONDARY HYPERPARATHYROIDISM IN PATIENTS WITH TYPE 1 DIABETES MELLITUS WITH DIABETIC NEPHROPATHY Бюллетень сибирской медицины type 1 diabetes mellitus diabetic nephropathy secondary hyperparathyroidism |
| title | FACTORS ASSOCIATED WITH THE DEVELOPMENT OF SECONDARY HYPERPARATHYROIDISM IN PATIENTS WITH TYPE 1 DIABETES MELLITUS WITH DIABETIC NEPHROPATHY |
| title_full | FACTORS ASSOCIATED WITH THE DEVELOPMENT OF SECONDARY HYPERPARATHYROIDISM IN PATIENTS WITH TYPE 1 DIABETES MELLITUS WITH DIABETIC NEPHROPATHY |
| title_fullStr | FACTORS ASSOCIATED WITH THE DEVELOPMENT OF SECONDARY HYPERPARATHYROIDISM IN PATIENTS WITH TYPE 1 DIABETES MELLITUS WITH DIABETIC NEPHROPATHY |
| title_full_unstemmed | FACTORS ASSOCIATED WITH THE DEVELOPMENT OF SECONDARY HYPERPARATHYROIDISM IN PATIENTS WITH TYPE 1 DIABETES MELLITUS WITH DIABETIC NEPHROPATHY |
| title_short | FACTORS ASSOCIATED WITH THE DEVELOPMENT OF SECONDARY HYPERPARATHYROIDISM IN PATIENTS WITH TYPE 1 DIABETES MELLITUS WITH DIABETIC NEPHROPATHY |
| title_sort | factors associated with the development of secondary hyperparathyroidism in patients with type 1 diabetes mellitus with diabetic nephropathy |
| topic | type 1 diabetes mellitus diabetic nephropathy secondary hyperparathyroidism |
| url | https://bulletin.ssmu.ru/jour/article/view/30 |
| work_keys_str_mv | AT yeakhantakova factorsassociatedwiththedevelopmentofsecondaryhyperparathyroidisminpatientswithtype1diabetesmellituswithdiabeticnephropathy |