Efficacy and safety of HYYK formula for residual follicle revival in premature ovarian insufficiency: a multicenter, randomized, double-blind, placebo-controlled trial protocol

Efficacy and safety of HYYK formula for residual follicle revival in premature ovarian insufficiency: a multicenter, randomized, double-blind, placebo-controlled trial protocol

Abstract Background Premature ovarian insufficiency (POI), a condition impacting women under 40, is rising globally, posing significant risks to fertility, bone health, and cardiovascular function. Conventional hormone replacement therapy (HRT) alleviates symptoms but fails to restore ovarian functi...

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Bibliographic Details
Main Authors: Yin Peng, Jian Liu, Yang Li, Guangning Nie, Fangping Cheng, Daning Feng, Qiaolin Du, Jian Huang, Hongyan Yang
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Premature ovarian insufficiency (POI)
Traditional Chinese medicine (TCM)
Residual follicle
Randomized controlled trial
Online Access:https://doi.org/10.1186/s12906-025-04803-3
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