Movement disorders that occurred as late manifestations of Alzheimer’s disease controlled by a low dose of carbamazepine
Introduction: According to the World Health Organization, 44 million people worldwide suffer from Alzheimer’s disease. Abnormal movements are atypical symptoms of Alzheimer’s disease. Case description: An 87-year-old woman, followed for Alzheimer’s disease, experienced abnormal movements. The episod...
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| Format: | Article |
| Language: | English |
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SMC MEDIA SRL
2024-12-01
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| Series: | European Journal of Case Reports in Internal Medicine |
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| Online Access: | https://www.ejcrim.com/index.php/EJCRIM/article/view/4943 |
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| author | Patrick Manckoundia Jérémie Vovelle Sylvia Cancemi Rachid Mahmoudi Thomas Renoncourt |
| author_facet | Patrick Manckoundia Jérémie Vovelle Sylvia Cancemi Rachid Mahmoudi Thomas Renoncourt |
| author_sort | Patrick Manckoundia |
| collection | DOAJ |
| description | Introduction: According to the World Health Organization, 44 million people worldwide suffer from Alzheimer’s disease. Abnormal movements are atypical symptoms of Alzheimer’s disease.
Case description: An 87-year-old woman, followed for Alzheimer’s disease, experienced abnormal movements. The episodes lasted 30 minutes, were involuntary, uncontrollable, anarchic, predominantly in the upper limbs, and without loss of consciousness or bladder control. An electroencephalogram ruled out atypical epilepsy. Pharmacovigilance investigation ruled out a drug-related cause. Magnetic resonance imaging revealed abnormalities suggestive of Alzheimer’s disease, with no other evidence to explain the abnormal movements. Apart from the presence of Alzheimer’s disease biomarkers, cerebrospinal fluid analysis found no abnormality. Dopamine transporter scan rule out an atypical parkinsonian syndrome. Finally, abnormal movements associated with Alzheimer’s disease were suspected. Abnormal movements disappeared within 72 hours on low-dose carbamazepine.
Conclusion: This case is educational both because of the clinical presentation and the management of symptoms. |
| format | Article |
| id | doaj-art-dad3d729ccf146229c4147129dddab9a |
| institution | Kabale University |
| issn | 2284-2594 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | SMC MEDIA SRL |
| record_format | Article |
| series | European Journal of Case Reports in Internal Medicine |
| spelling | doaj-art-dad3d729ccf146229c4147129dddab9a2025-01-07T13:40:28ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942024-12-0110.12890/2024_0049434478Movement disorders that occurred as late manifestations of Alzheimer’s disease controlled by a low dose of carbamazepinePatrick Manckoundia0Jérémie Vovelle1Sylvia Cancemi2Rachid Mahmoudi3Thomas Renoncourt4Department of Geriatrics and Internal Medicine, Champmaillot Hospital, University Hospital, Dijon, France; UMR Inserm/U1093 Cognition, Action, Sensorimotor Plasticity, University of Burgundy and Franche Comté, Dijon, FranceDepartment of Geriatrics and Internal Medicine, Champmaillot Hospital, University Hospital, Dijon, FranceDepartment of Medical Care and Rehabilitation in Geriatrics, University Hospital, Dijon, FranceDepartment of Internal Medicine and Acute Geriatrics, University Hospital, Reims, FranceDepartment of Geriatrics and Internal Medicine, Champmaillot Hospital, University Hospital, Dijon, France; UMR Inserm/U1093 Cognition, Action, Sensorimotor Plasticity, University of Burgundy and Franche Comté, Dijon, FranceIntroduction: According to the World Health Organization, 44 million people worldwide suffer from Alzheimer’s disease. Abnormal movements are atypical symptoms of Alzheimer’s disease. Case description: An 87-year-old woman, followed for Alzheimer’s disease, experienced abnormal movements. The episodes lasted 30 minutes, were involuntary, uncontrollable, anarchic, predominantly in the upper limbs, and without loss of consciousness or bladder control. An electroencephalogram ruled out atypical epilepsy. Pharmacovigilance investigation ruled out a drug-related cause. Magnetic resonance imaging revealed abnormalities suggestive of Alzheimer’s disease, with no other evidence to explain the abnormal movements. Apart from the presence of Alzheimer’s disease biomarkers, cerebrospinal fluid analysis found no abnormality. Dopamine transporter scan rule out an atypical parkinsonian syndrome. Finally, abnormal movements associated with Alzheimer’s disease were suspected. Abnormal movements disappeared within 72 hours on low-dose carbamazepine. Conclusion: This case is educational both because of the clinical presentation and the management of symptoms.https://www.ejcrim.com/index.php/EJCRIM/article/view/4943abnormal movementsalzheimer’s diseasemanagement |
| spellingShingle | Patrick Manckoundia Jérémie Vovelle Sylvia Cancemi Rachid Mahmoudi Thomas Renoncourt Movement disorders that occurred as late manifestations of Alzheimer’s disease controlled by a low dose of carbamazepine European Journal of Case Reports in Internal Medicine abnormal movements alzheimer’s disease management |
| title | Movement disorders that occurred as late manifestations of Alzheimer’s disease controlled by a low dose of carbamazepine |
| title_full | Movement disorders that occurred as late manifestations of Alzheimer’s disease controlled by a low dose of carbamazepine |
| title_fullStr | Movement disorders that occurred as late manifestations of Alzheimer’s disease controlled by a low dose of carbamazepine |
| title_full_unstemmed | Movement disorders that occurred as late manifestations of Alzheimer’s disease controlled by a low dose of carbamazepine |
| title_short | Movement disorders that occurred as late manifestations of Alzheimer’s disease controlled by a low dose of carbamazepine |
| title_sort | movement disorders that occurred as late manifestations of alzheimer s disease controlled by a low dose of carbamazepine |
| topic | abnormal movements alzheimer’s disease management |
| url | https://www.ejcrim.com/index.php/EJCRIM/article/view/4943 |
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