Infection <i>Helicobacter pylori</i> and stomach cancer: state-of-the-art

The aim of review. To carry out analysis of the publications devoted to Helicobacter pylori infection and stomach cancer (SC) interrelation.Original positions. Available data convincingly confirm that Н. pylori infection increases risk of SC development, however in close interaction with host factor...

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Main Author: A. A. Sheptulin
Format: Article
Language:Russian
Published: Gastro LLC 2012-04-01
Series:Российский журнал гастроэнтерологии, гепатологии, колопроктологии
Subjects:
Online Access:https://www.gastro-j.ru/jour/article/view/1281
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author A. A. Sheptulin
author_facet A. A. Sheptulin
author_sort A. A. Sheptulin
collection DOAJ
description The aim of review. To carry out analysis of the publications devoted to Helicobacter pylori infection and stomach cancer (SC) interrelation.Original positions. Available data convincingly confirm that Н. pylori infection increases risk of SC development, however in close interaction with host factors – genetic factors, dietary habits, etc. Eradication of Н. pylori results in decrease of atrophic gastritis severity, but does not affect intestinal metaplasia process. Nowadays it is indicated for patients with high risk of SC (having atrophic gastritis, postgastrectomy patients for early SC, first-degree relatives of patients with SC).Conclusion. Pathophysiological and clinical aspects of interrelations between Н. pylori infection and SC require the further studies.
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series Российский журнал гастроэнтерологии, гепатологии, колопроктологии
spelling doaj-art-daca45f9732342bab0c32f89d7909ddf2025-02-10T16:14:32ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732012-04-012227782858Infection <i>Helicobacter pylori</i> and stomach cancer: state-of-the-artA. A. Sheptulin0Первый Московский государственный медицинский университет им. И.М. СеченоваThe aim of review. To carry out analysis of the publications devoted to Helicobacter pylori infection and stomach cancer (SC) interrelation.Original positions. Available data convincingly confirm that Н. pylori infection increases risk of SC development, however in close interaction with host factors – genetic factors, dietary habits, etc. Eradication of Н. pylori results in decrease of atrophic gastritis severity, but does not affect intestinal metaplasia process. Nowadays it is indicated for patients with high risk of SC (having atrophic gastritis, postgastrectomy patients for early SC, first-degree relatives of patients with SC).Conclusion. Pathophysiological and clinical aspects of interrelations between Н. pylori infection and SC require the further studies.https://www.gastro-j.ru/jour/article/view/1281helicobacter pyloristomach cancerindications for eradication
spellingShingle A. A. Sheptulin
Infection <i>Helicobacter pylori</i> and stomach cancer: state-of-the-art
Российский журнал гастроэнтерологии, гепатологии, колопроктологии
helicobacter pylori
stomach cancer
indications for eradication
title Infection <i>Helicobacter pylori</i> and stomach cancer: state-of-the-art
title_full Infection <i>Helicobacter pylori</i> and stomach cancer: state-of-the-art
title_fullStr Infection <i>Helicobacter pylori</i> and stomach cancer: state-of-the-art
title_full_unstemmed Infection <i>Helicobacter pylori</i> and stomach cancer: state-of-the-art
title_short Infection <i>Helicobacter pylori</i> and stomach cancer: state-of-the-art
title_sort infection i helicobacter pylori i and stomach cancer state of the art
topic helicobacter pylori
stomach cancer
indications for eradication
url https://www.gastro-j.ru/jour/article/view/1281
work_keys_str_mv AT aasheptulin infectionihelicobacterpyloriiandstomachcancerstateoftheart