Correlation between Methicillin-Resistant Staphylococcus aureus Infection with Length of Stay and Mortality at Gunung Jati Regional Hospital, Cirebon, Indonesia: A Case Control Study with Total Sampling
Background: In 2017, WHO identified Methicillin-Resistant Staphylococcus aureus (MRSA) as a high-priority pathogen due to its antimicrobial resistance. MRSA prevalence has been rising since the 1960s, reaching 20% globally and over 80% in some countries. This increasing prevalence of MRSA is accomp...
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Yayasan Aliansi Cendekiawan Indonesia Thailand
2024-12-01
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| Series: | GHMJ (Global Health Management Journal) |
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| Online Access: | https://publications.inschool.id/index.php/ghmj/article/view/1116 |
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| author | Ranidaa' Diyaa' Azmi Mohammad Erwin Indrakusuma Taufan Herwindo Dewangga |
| author_facet | Ranidaa' Diyaa' Azmi Mohammad Erwin Indrakusuma Taufan Herwindo Dewangga |
| author_sort | Ranidaa' Diyaa' Azmi |
| collection | DOAJ |
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Background: In 2017, WHO identified Methicillin-Resistant Staphylococcus aureus (MRSA) as a high-priority pathogen due to its antimicrobial resistance. MRSA prevalence has been rising since the 1960s, reaching 20% globally and over 80% in some countries. This increasing prevalence of MRSA is accompanied by higher morbidity, more challenging management with difficult treatment, and prolonged length of stay, and consequently increased mortality risk.
Aims: To determine the relationship between MRSA infection with length of stay and mortality at Gunung Jati Regional Hospital, Cirebon, Indonesia.
Methods: A case-control study was performed in 46 cases and 92 controls. This study used total sampling including 138 samples, selected population of MRSA patients between 2021-2023 at Gunung Jati Regional Hospital, Cirebon. Data was taken from medical record and WHONET data.
Results: The Mann-Whitney test results showed a significant correlation between MRSA infection and the length of stay compared to MSSA infection (p=0.003). Furthermore, the Chi-Square test revealed a significant correlation between MRSA infection and mortality (p=0.019; OR, 2.448; 95% CI, 1.151 – 5.205).
Conclusion: Methicillin-Resistant Staphylococcus aureus infection is associated with a longer length of stay and higher mortality compared to Methicillin-Sensitive Staphylococcus aureus infection.
Received: 25 September 2024 | Reviewed: 21 October 2024 |
Revised: 30 November 2024 | Accepted: 15 December 2024.
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| format | Article |
| id | doaj-art-dac9919820ba4972a40cd4fdb953ba75 |
| institution | DOAJ |
| issn | 2580-9296 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Yayasan Aliansi Cendekiawan Indonesia Thailand |
| record_format | Article |
| series | GHMJ (Global Health Management Journal) |
| spelling | doaj-art-dac9919820ba4972a40cd4fdb953ba752025-08-20T02:49:18ZengYayasan Aliansi Cendekiawan Indonesia ThailandGHMJ (Global Health Management Journal)2580-92962024-12-017410.35898/ghmj-741116Correlation between Methicillin-Resistant Staphylococcus aureus Infection with Length of Stay and Mortality at Gunung Jati Regional Hospital, Cirebon, Indonesia: A Case Control Study with Total SamplingRanidaa' Diyaa' Azmi0https://orcid.org/0009-0009-3177-0802Mohammad Erwin Indrakusuma1https://orcid.org/0009-0002-7587-4186Taufan Herwindo Dewangga2https://orcid.org/0000-0002-9457-9820Department of Clinical Microbiology, Faculty of Medicine, Universitas Swadaya Gunung Jati, IndonesiaDepartment of Clinical Microbiology, Faculty of Medicine, Universitas Swadaya Gunung Jati, IndonesiaDepartment of Orthopaedic and Traumatology, Faculty of Medicine, Universitas Swadaya Gunung Jati, Indonesia Background: In 2017, WHO identified Methicillin-Resistant Staphylococcus aureus (MRSA) as a high-priority pathogen due to its antimicrobial resistance. MRSA prevalence has been rising since the 1960s, reaching 20% globally and over 80% in some countries. This increasing prevalence of MRSA is accompanied by higher morbidity, more challenging management with difficult treatment, and prolonged length of stay, and consequently increased mortality risk. Aims: To determine the relationship between MRSA infection with length of stay and mortality at Gunung Jati Regional Hospital, Cirebon, Indonesia. Methods: A case-control study was performed in 46 cases and 92 controls. This study used total sampling including 138 samples, selected population of MRSA patients between 2021-2023 at Gunung Jati Regional Hospital, Cirebon. Data was taken from medical record and WHONET data. Results: The Mann-Whitney test results showed a significant correlation between MRSA infection and the length of stay compared to MSSA infection (p=0.003). Furthermore, the Chi-Square test revealed a significant correlation between MRSA infection and mortality (p=0.019; OR, 2.448; 95% CI, 1.151 – 5.205). Conclusion: Methicillin-Resistant Staphylococcus aureus infection is associated with a longer length of stay and higher mortality compared to Methicillin-Sensitive Staphylococcus aureus infection. Received: 25 September 2024 | Reviewed: 21 October 2024 | Revised: 30 November 2024 | Accepted: 15 December 2024. https://publications.inschool.id/index.php/ghmj/article/view/1116Methicillin-Resistant Staphylococcus aureus (MRSA)Methicillin-Sensitive Staphylococcus aureus (MSSA)Length of StayMortality |
| spellingShingle | Ranidaa' Diyaa' Azmi Mohammad Erwin Indrakusuma Taufan Herwindo Dewangga Correlation between Methicillin-Resistant Staphylococcus aureus Infection with Length of Stay and Mortality at Gunung Jati Regional Hospital, Cirebon, Indonesia: A Case Control Study with Total Sampling GHMJ (Global Health Management Journal) Methicillin-Resistant Staphylococcus aureus (MRSA) Methicillin-Sensitive Staphylococcus aureus (MSSA) Length of Stay Mortality |
| title | Correlation between Methicillin-Resistant Staphylococcus aureus Infection with Length of Stay and Mortality at Gunung Jati Regional Hospital, Cirebon, Indonesia: A Case Control Study with Total Sampling |
| title_full | Correlation between Methicillin-Resistant Staphylococcus aureus Infection with Length of Stay and Mortality at Gunung Jati Regional Hospital, Cirebon, Indonesia: A Case Control Study with Total Sampling |
| title_fullStr | Correlation between Methicillin-Resistant Staphylococcus aureus Infection with Length of Stay and Mortality at Gunung Jati Regional Hospital, Cirebon, Indonesia: A Case Control Study with Total Sampling |
| title_full_unstemmed | Correlation between Methicillin-Resistant Staphylococcus aureus Infection with Length of Stay and Mortality at Gunung Jati Regional Hospital, Cirebon, Indonesia: A Case Control Study with Total Sampling |
| title_short | Correlation between Methicillin-Resistant Staphylococcus aureus Infection with Length of Stay and Mortality at Gunung Jati Regional Hospital, Cirebon, Indonesia: A Case Control Study with Total Sampling |
| title_sort | correlation between methicillin resistant staphylococcus aureus infection with length of stay and mortality at gunung jati regional hospital cirebon indonesia a case control study with total sampling |
| topic | Methicillin-Resistant Staphylococcus aureus (MRSA) Methicillin-Sensitive Staphylococcus aureus (MSSA) Length of Stay Mortality |
| url | https://publications.inschool.id/index.php/ghmj/article/view/1116 |
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