Visualization of implanted GL261 glioma cells in living mouse brain slices using fluorescent 4-(4-(dimethylamino)-styryl)-N-methylpyridinium iodide (ASP+)

Visualization of implanted GL261 glioma cells in living mouse brain slices using fluorescent 4-(4-(dimethylamino)-styryl)-N-methylpyridinium iodide (ASP+)

Here we describe a new method of glioma cell visualization in living brain slices that can be used for evaluation of tumor size or visualization of internal tumor structures. Glial cells, as well as glioma cells of glial origin, express high levels of organic cation transporters. We demonstrate that...

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Bibliographic Details
Main Authors: Lilia Y. Kucheryavykh, Yuriy V. Kucheryavykh, Kimberleve Rolón-Reyes, Serguei N. Skatchkov, Misty J. Eaton, Luis A. Cubano, Mikhail Inyushin
Format: Article
Language:English
Published: Taylor & Francis Group 2012-11-01
Series:BioTechniques
Subjects:
glioma
ASP+
brain slices
fluorescent imaging
Online Access:https://www.future-science.com/doi/10.2144/000113940
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