HNGF6A ameliorates oxidative stress-mediated mitochondrial dysfunction in degenerative meniscus

HNGF6A ameliorates oxidative stress-mediated mitochondrial dysfunction in degenerative meniscus

Aims: Meniscus injury can lead to knee synovitis and cartilage deterioration, ultimately resulting in osteoarthritis (OA). Mitochondrial dysfunction has been identified as an induction factor in OA development, owing to an imbalance between the production of reactive oxygen species (ROS) and the an...

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Bibliographic Details
Main Authors: Ruonan Liu, Xue Du, Yufeng Chen, Zijing Zhu, Zongrui Jiang, Chengyun Zhang, Dong Jiang, Zhiqi Zhang
Format: Article
Language:English
Published: The British Editorial Society of Bone & Joint Surgery 2025-04-01
Series:Bone & Joint Research
Subjects:
osteoarthritis
meniscal degeneration
mitochondrial damage
oxidative stress
meniscus
meniscus cells
autophagy
apoptosis
osteoarthritis (oa)
osteophytes
knee joints
peptide
destabilization of the medial meniscus (dmm)
Online Access:https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.144.BJR-2024-0318.R1
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