Analysis of Pregnancy Outcomes in Women with Polycystic Ovary Syndrome (PCOS): A Retrospective Study

Introduction: Although PCOS affects reproductive health, its consequences on the outcome of pregnancies are still up for discussion. Comparing the pregnancy outcomes of women with PCOS to a control group was the goal of this retrospective research. Methods: Analysis of data from tertiary care center...

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Main Authors: Manjula Salgotra, Nancy Bharti, Varsha Sinha, Rahul Tiwari, Heena Dixit Tiwari, Chapala Shashank, Jasmine Kalsi, Priyanka R Pujari
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-08-01
Series:Journal of Pharmacy and Bioallied Sciences
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Online Access:https://journals.lww.com/10.4103/jpbs.jpbs_233_24
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author Manjula Salgotra
Nancy Bharti
Varsha Sinha
Rahul Tiwari
Heena Dixit Tiwari
Chapala Shashank
Jasmine Kalsi
Priyanka R Pujari
author_facet Manjula Salgotra
Nancy Bharti
Varsha Sinha
Rahul Tiwari
Heena Dixit Tiwari
Chapala Shashank
Jasmine Kalsi
Priyanka R Pujari
author_sort Manjula Salgotra
collection DOAJ
description Introduction: Although PCOS affects reproductive health, its consequences on the outcome of pregnancies are still up for discussion. Comparing the pregnancy outcomes of women with PCOS to a control group was the goal of this retrospective research. Methods: Analysis of data from tertiary care centers between 2017 and 2022 was done in retrospective. While the controls (n = 300) matched for age, BMI, and parity, the PCOS group (n = 300) satisfied Rotterdam criteria. Maternal-fetal health, birth outcomes, and gestational problems were evaluated. Results: Compared to controls, women with PCOS had a greater incidence of preeclampsia (12.3% vs. 8.1%, P = 0.023) and gestational diabetes (18.7% vs. 9.8%, P < 0.001). On the other hand, there were no notable variations in low birth weight (P = 0.589) or preterm delivery (P = 0.321). Conclusion: In summary, the correlation between PCOS and increased risks of gestational diabetes and preeclampsia emphasizes the necessity of customized therapies. The intricacy of PCOS’s influence on birth outcomes is shown by the inconclusive results regarding preterm delivery and low birth weight, which call for more research to enhance mother and newborn health in this group.
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spelling doaj-art-dac793c9ef784d93a5f5eca1c49bae4a2025-08-20T01:48:07ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0976-48790975-74062024-08-0116Suppl 3S2767S276910.4103/jpbs.jpbs_233_24Analysis of Pregnancy Outcomes in Women with Polycystic Ovary Syndrome (PCOS): A Retrospective StudyManjula SalgotraNancy BhartiVarsha SinhaRahul TiwariHeena Dixit TiwariChapala ShashankJasmine KalsiPriyanka R PujariIntroduction: Although PCOS affects reproductive health, its consequences on the outcome of pregnancies are still up for discussion. Comparing the pregnancy outcomes of women with PCOS to a control group was the goal of this retrospective research. Methods: Analysis of data from tertiary care centers between 2017 and 2022 was done in retrospective. While the controls (n = 300) matched for age, BMI, and parity, the PCOS group (n = 300) satisfied Rotterdam criteria. Maternal-fetal health, birth outcomes, and gestational problems were evaluated. Results: Compared to controls, women with PCOS had a greater incidence of preeclampsia (12.3% vs. 8.1%, P = 0.023) and gestational diabetes (18.7% vs. 9.8%, P < 0.001). On the other hand, there were no notable variations in low birth weight (P = 0.589) or preterm delivery (P = 0.321). Conclusion: In summary, the correlation between PCOS and increased risks of gestational diabetes and preeclampsia emphasizes the necessity of customized therapies. The intricacy of PCOS’s influence on birth outcomes is shown by the inconclusive results regarding preterm delivery and low birth weight, which call for more research to enhance mother and newborn health in this group.https://journals.lww.com/10.4103/jpbs.jpbs_233_24birth outcomesgestational complicationsmaternal-fetal healthpolycystic ovary syndromepregnancy outcomes
spellingShingle Manjula Salgotra
Nancy Bharti
Varsha Sinha
Rahul Tiwari
Heena Dixit Tiwari
Chapala Shashank
Jasmine Kalsi
Priyanka R Pujari
Analysis of Pregnancy Outcomes in Women with Polycystic Ovary Syndrome (PCOS): A Retrospective Study
Journal of Pharmacy and Bioallied Sciences
birth outcomes
gestational complications
maternal-fetal health
polycystic ovary syndrome
pregnancy outcomes
title Analysis of Pregnancy Outcomes in Women with Polycystic Ovary Syndrome (PCOS): A Retrospective Study
title_full Analysis of Pregnancy Outcomes in Women with Polycystic Ovary Syndrome (PCOS): A Retrospective Study
title_fullStr Analysis of Pregnancy Outcomes in Women with Polycystic Ovary Syndrome (PCOS): A Retrospective Study
title_full_unstemmed Analysis of Pregnancy Outcomes in Women with Polycystic Ovary Syndrome (PCOS): A Retrospective Study
title_short Analysis of Pregnancy Outcomes in Women with Polycystic Ovary Syndrome (PCOS): A Retrospective Study
title_sort analysis of pregnancy outcomes in women with polycystic ovary syndrome pcos a retrospective study
topic birth outcomes
gestational complications
maternal-fetal health
polycystic ovary syndrome
pregnancy outcomes
url https://journals.lww.com/10.4103/jpbs.jpbs_233_24
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