ASSOCIATION BETWEEN VITAMIN D AND URIC ACID AMONG NORTH CYPRUS ADULTS: FIRST PRELIMINARY REPORT
Objective: The aim of the study is to evaluate the association between serum uric acid (SUA) and 25-OH Vitamin D (25-OH-VIT D). There is no data about the association between hyperuricemia and 25-OH-VIT D deficiency for North Cyprus. Material and Methods: A cross-sectional study was performed on 356...
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Istanbul University Press
2022-10-01
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| Series: | İstanbul Tıp Fakültesi Dergisi |
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| Online Access: | https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/F536BCDDC1FC481BBD644C5A1F30C69C |
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| author | Mehtap Tınazlı Nuriye Sancar Meryem Güvenir Deniz Granit Semavi |
| author_facet | Mehtap Tınazlı Nuriye Sancar Meryem Güvenir Deniz Granit Semavi |
| author_sort | Mehtap Tınazlı |
| collection | DOAJ |
| description | Objective: The aim of the study is to evaluate the association between serum uric acid (SUA) and 25-OH Vitamin D (25-OH-VIT D). There is no data about the association between hyperuricemia and 25-OH-VIT D deficiency for North Cyprus. Material and Methods: A cross-sectional study was performed on 356 adults aged between 18-75 years in the North Cyprus. Patients socio-demographic information, clinical and biochemical characteristics, eating habits, and lifestyle choices were recorded. Biochemical parameters were evaluated in all patients. Data were analysed by Chi-square test, Student’s t test, and ANOVA, as appropriate. Also, the Gamma correlation coefficient was calculated for the relationship between 25-OH Vitamin D groups and the other variables. Results: The prevalence of 25-OH-VIT D deficiency was 55.9% among the patients (12.86±4.63 ng/mL), the prevalence of 25-OH-VIT D insufficiency (23.44±2.38 ng/mL) was 27%, and 25-OH-VIT D levels were sufficient in only 17.1% of the patients (36.01±5.83 ng/mL). The ANOVA results indicated statistically significant differences SUA for both male and female patients between the 25-OH-VIT D groups. According to the Gamma correlation coefficient values, 25-OH Vitamin D levels were significantly negatively correlated with SUA. Conclusion: In our study indicated a high prevalence of 25-OHVIT D deficiency and insufficiency in North Cyprus adults and we have found a significant association between SUA levels and 25-OH-VIT D. As a result, both vitamin D supplementation and uric acid-lowering therapies are important in protecting patients against future atherosclerotic diseases. |
| format | Article |
| id | doaj-art-dac67c2681534550aa8c348caf201d57 |
| institution | OA Journals |
| issn | 1305-6441 |
| language | English |
| publishDate | 2022-10-01 |
| publisher | Istanbul University Press |
| record_format | Article |
| series | İstanbul Tıp Fakültesi Dergisi |
| spelling | doaj-art-dac67c2681534550aa8c348caf201d572025-08-20T01:50:27ZengIstanbul University Pressİstanbul Tıp Fakültesi Dergisi1305-64412022-10-0185456457110.26650/IUITFD.1078093123456ASSOCIATION BETWEEN VITAMIN D AND URIC ACID AMONG NORTH CYPRUS ADULTS: FIRST PRELIMINARY REPORTMehtap Tınazlı0https://orcid.org/0000-0002-9702-9947Nuriye Sancar1https://orcid.org/0000-0002-4276-4653Meryem Güvenir2https://orcid.org/0000-0002-7858-0696Deniz Granit Semavi3https://orcid.org/0000-0001-8614-6323Yakın Doğu Üniversitesi, Nicosia, CyprusYakın Doğu Üniversitesi, Nicosia, CyprusYakın Doğu Üniversitesi, Nicosia, CyprusYakın Doğu Üniversitesi, Nicosia, CyprusObjective: The aim of the study is to evaluate the association between serum uric acid (SUA) and 25-OH Vitamin D (25-OH-VIT D). There is no data about the association between hyperuricemia and 25-OH-VIT D deficiency for North Cyprus. Material and Methods: A cross-sectional study was performed on 356 adults aged between 18-75 years in the North Cyprus. Patients socio-demographic information, clinical and biochemical characteristics, eating habits, and lifestyle choices were recorded. Biochemical parameters were evaluated in all patients. Data were analysed by Chi-square test, Student’s t test, and ANOVA, as appropriate. Also, the Gamma correlation coefficient was calculated for the relationship between 25-OH Vitamin D groups and the other variables. Results: The prevalence of 25-OH-VIT D deficiency was 55.9% among the patients (12.86±4.63 ng/mL), the prevalence of 25-OH-VIT D insufficiency (23.44±2.38 ng/mL) was 27%, and 25-OH-VIT D levels were sufficient in only 17.1% of the patients (36.01±5.83 ng/mL). The ANOVA results indicated statistically significant differences SUA for both male and female patients between the 25-OH-VIT D groups. According to the Gamma correlation coefficient values, 25-OH Vitamin D levels were significantly negatively correlated with SUA. Conclusion: In our study indicated a high prevalence of 25-OHVIT D deficiency and insufficiency in North Cyprus adults and we have found a significant association between SUA levels and 25-OH-VIT D. As a result, both vitamin D supplementation and uric acid-lowering therapies are important in protecting patients against future atherosclerotic diseases.https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/F536BCDDC1FC481BBD644C5A1F30C69Cnorth cyprusvitamin duric acidprevalenceatherosclerosis |
| spellingShingle | Mehtap Tınazlı Nuriye Sancar Meryem Güvenir Deniz Granit Semavi ASSOCIATION BETWEEN VITAMIN D AND URIC ACID AMONG NORTH CYPRUS ADULTS: FIRST PRELIMINARY REPORT İstanbul Tıp Fakültesi Dergisi north cyprus vitamin d uric acid prevalence atherosclerosis |
| title | ASSOCIATION BETWEEN VITAMIN D AND URIC ACID AMONG NORTH CYPRUS ADULTS: FIRST PRELIMINARY REPORT |
| title_full | ASSOCIATION BETWEEN VITAMIN D AND URIC ACID AMONG NORTH CYPRUS ADULTS: FIRST PRELIMINARY REPORT |
| title_fullStr | ASSOCIATION BETWEEN VITAMIN D AND URIC ACID AMONG NORTH CYPRUS ADULTS: FIRST PRELIMINARY REPORT |
| title_full_unstemmed | ASSOCIATION BETWEEN VITAMIN D AND URIC ACID AMONG NORTH CYPRUS ADULTS: FIRST PRELIMINARY REPORT |
| title_short | ASSOCIATION BETWEEN VITAMIN D AND URIC ACID AMONG NORTH CYPRUS ADULTS: FIRST PRELIMINARY REPORT |
| title_sort | association between vitamin d and uric acid among north cyprus adults first preliminary report |
| topic | north cyprus vitamin d uric acid prevalence atherosclerosis |
| url | https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/F536BCDDC1FC481BBD644C5A1F30C69C |
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