A Glucagonoma Presenting as Cerebral Vein Thrombosis and Diabetes
Glucagonomas are rare pancreatic neuroendocrine tumors (pNETs), malignant in 80% of cases, thus highlighting the importance of early diagnosis and treatment. Primary manifestations are diabetes, dermatosis, depression, weight loss, and deep vein thrombosis. Unlike other pNETs, glucagonomas are assoc...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2022/7659341 |
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| author | Marina Delli Colli Bader N. Alamri Laura Palma Juan Rivera |
| author_facet | Marina Delli Colli Bader N. Alamri Laura Palma Juan Rivera |
| author_sort | Marina Delli Colli |
| collection | DOAJ |
| description | Glucagonomas are rare pancreatic neuroendocrine tumors (pNETs), malignant in 80% of cases, thus highlighting the importance of early diagnosis and treatment. Primary manifestations are diabetes, dermatosis, depression, weight loss, and deep vein thrombosis. Unlike other pNETs, glucagonomas are associated with a higher incidence of thromboembolic events, often resulting in death. We present the case of a glucagonoma patient whose primary manifestation was cerebral sinus venous thrombosis (CS-VT). Early diagnosis enabled curative resection. The purpose of this paper is to review the underlying mechanisms associated with increased coagulopathy in glucagonomas. |
| format | Article |
| id | doaj-art-dab37f96b2b4463098b46003bfd04841 |
| institution | Kabale University |
| issn | 2090-651X |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-dab37f96b2b4463098b46003bfd048412025-02-03T01:22:13ZengWileyCase Reports in Endocrinology2090-651X2022-01-01202210.1155/2022/7659341A Glucagonoma Presenting as Cerebral Vein Thrombosis and DiabetesMarina Delli Colli0Bader N. Alamri1Laura Palma2Juan Rivera3Division of Endocrinology and MetabolismDivision of Endocrinology and MetabolismDivision of Medical GeneticsDivision of Endocrinology and MetabolismGlucagonomas are rare pancreatic neuroendocrine tumors (pNETs), malignant in 80% of cases, thus highlighting the importance of early diagnosis and treatment. Primary manifestations are diabetes, dermatosis, depression, weight loss, and deep vein thrombosis. Unlike other pNETs, glucagonomas are associated with a higher incidence of thromboembolic events, often resulting in death. We present the case of a glucagonoma patient whose primary manifestation was cerebral sinus venous thrombosis (CS-VT). Early diagnosis enabled curative resection. The purpose of this paper is to review the underlying mechanisms associated with increased coagulopathy in glucagonomas.http://dx.doi.org/10.1155/2022/7659341 |
| spellingShingle | Marina Delli Colli Bader N. Alamri Laura Palma Juan Rivera A Glucagonoma Presenting as Cerebral Vein Thrombosis and Diabetes Case Reports in Endocrinology |
| title | A Glucagonoma Presenting as Cerebral Vein Thrombosis and Diabetes |
| title_full | A Glucagonoma Presenting as Cerebral Vein Thrombosis and Diabetes |
| title_fullStr | A Glucagonoma Presenting as Cerebral Vein Thrombosis and Diabetes |
| title_full_unstemmed | A Glucagonoma Presenting as Cerebral Vein Thrombosis and Diabetes |
| title_short | A Glucagonoma Presenting as Cerebral Vein Thrombosis and Diabetes |
| title_sort | glucagonoma presenting as cerebral vein thrombosis and diabetes |
| url | http://dx.doi.org/10.1155/2022/7659341 |
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