Structures of an apo and a binary complex of an evolved archeal B family DNA polymerase capable of synthesising highly cy-dye labelled DNA.
Thermophilic DNA polymerases of the polB family are of great importance in biotechnological applications including high-fidelity PCR. Of particular interest is the relative promiscuity of engineered versions of the exo- form of polymerases from the Thermo- and Pyrococcales families towards non-canon...
Saved in:
| Main Authors: | Samantha A Wynne, Vitor B Pinheiro, Philipp Holliger, Andrew G W Leslie |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2013-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0070892 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Comparison of the sequence-dependent fluorescence of the cyanine dyes Cy3, Cy5, DyLight DY547 and DyLight DY647 on single-stranded DNA.
by: Nicole Kretschy, et al.
Published: (2014-01-01) -
Isothermal Amplification and Multimerization of DNA by Bst DNA Polymerase
by: G.J. Hafner, et al.
Published: (2001-04-01) -
DNA Polymerase Gamma in Mitochondrial DNA Replication and Repair
by: William C. Copeland, et al.
Published: (2003-01-01) -
DNA Polymerases as Engines for Biotechnology
by: Scott C. Hamilton, et al.
Published: (2001-08-01) -
Nsp1 stalls DNA polymerase α at DNA hairpins
by: Andrey G. Baranovskiy, et al.
Published: (2025-05-01)