Optimization and production of laccase enzyme by Bacillus cereus isolated from effluent of paint producing industry

Abstract Background Paint industry uses different coloured pigment that are known to contain heavy metals including titanium dioxide, iron oxides, aluminium, mica flakes, cadmium, mercury and lead. Laccase enzyme has been reported to have the ability to degrade heavy metals used in different industr...

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Main Authors: B. A. Oyedeji, N. R. Oloye, S. O. Adebajo, M. O. Taiwo, B. T. Folarin, A. K. Akintokun
Format: Article
Language:English
Published: SpringerOpen 2025-04-01
Series:Bulletin of the National Research Centre
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Online Access:https://doi.org/10.1186/s42269-025-01319-1
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author B. A. Oyedeji
N. R. Oloye
S. O. Adebajo
M. O. Taiwo
B. T. Folarin
A. K. Akintokun
author_facet B. A. Oyedeji
N. R. Oloye
S. O. Adebajo
M. O. Taiwo
B. T. Folarin
A. K. Akintokun
author_sort B. A. Oyedeji
collection DOAJ
description Abstract Background Paint industry uses different coloured pigment that are known to contain heavy metals including titanium dioxide, iron oxides, aluminium, mica flakes, cadmium, mercury and lead. Laccase enzyme has been reported to have the ability to degrade heavy metals used in different industries. Laccase enzyme is associated with a wide class of enzymes called polyphenol oxidases which are useful in industries such as wine and beverage, baking, textile, printing and tannery and pharmaceutical. Microorganisms produce enzymes such as laccase for bioremediation. This study is aimed at isolating bacteria from waste water of paint industry, screening for potential laccase producing bacteria and production of laccase enzyme. Methodology Bacteria were isolated from effluent from paint industry and were screened for laccase enzyme using 0.04% guaiacol. Bacteria with highest enzyme activity were used for optimization studies of temperature, pH, inoculum volume, substrate concentration and copper sulphate concentration. Duncan multiple range test was utilized to separate means after the experiments were conducted in triplicate. Data were analysed with Statistical Package for Social Sciences. Results Different bacteria were isolated but Bacillus cereus had the highest laccase enzyme activity after primary and secondary screening. Optimization of growth parameters showed that B. cereus had 0.0489 U/mL laccase activity as the highest. Synthesis of laccase enzyme was optimum at 5 days, pH 6.0, 35 °C temperature, 5% inoculum volume, 5 mM guaiacol concentration and 0.3 mM concentration of copper sulphate. Conclusion This study’s findings demonstrated that bacteria are found in paint industry effluent and these bacteria can produce laccase enzyme which can effectively be employed in bioremediation of soil contaminated by heavy metals present in effluents from paint industry thereby preventing environmental pollution.
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spelling doaj-art-daa3a89484c74941b2cab6ca0a33b8412025-08-20T02:20:06ZengSpringerOpenBulletin of the National Research Centre2522-83072025-04-0149111110.1186/s42269-025-01319-1Optimization and production of laccase enzyme by Bacillus cereus isolated from effluent of paint producing industryB. A. Oyedeji0N. R. Oloye1S. O. Adebajo2M. O. Taiwo3B. T. Folarin4A. K. Akintokun5Department of Microbiology, Chrisland UniversityDepartment of Microbiology, Federal University of AgricultureDepartment of Microbiology, Federal University of AgricultureDepartment of Microbiology, Chrisland UniversityDepartment of Chemistry, Chrisland UniversityDepartment of Microbiology, Federal University of AgricultureAbstract Background Paint industry uses different coloured pigment that are known to contain heavy metals including titanium dioxide, iron oxides, aluminium, mica flakes, cadmium, mercury and lead. Laccase enzyme has been reported to have the ability to degrade heavy metals used in different industries. Laccase enzyme is associated with a wide class of enzymes called polyphenol oxidases which are useful in industries such as wine and beverage, baking, textile, printing and tannery and pharmaceutical. Microorganisms produce enzymes such as laccase for bioremediation. This study is aimed at isolating bacteria from waste water of paint industry, screening for potential laccase producing bacteria and production of laccase enzyme. Methodology Bacteria were isolated from effluent from paint industry and were screened for laccase enzyme using 0.04% guaiacol. Bacteria with highest enzyme activity were used for optimization studies of temperature, pH, inoculum volume, substrate concentration and copper sulphate concentration. Duncan multiple range test was utilized to separate means after the experiments were conducted in triplicate. Data were analysed with Statistical Package for Social Sciences. Results Different bacteria were isolated but Bacillus cereus had the highest laccase enzyme activity after primary and secondary screening. Optimization of growth parameters showed that B. cereus had 0.0489 U/mL laccase activity as the highest. Synthesis of laccase enzyme was optimum at 5 days, pH 6.0, 35 °C temperature, 5% inoculum volume, 5 mM guaiacol concentration and 0.3 mM concentration of copper sulphate. Conclusion This study’s findings demonstrated that bacteria are found in paint industry effluent and these bacteria can produce laccase enzyme which can effectively be employed in bioremediation of soil contaminated by heavy metals present in effluents from paint industry thereby preventing environmental pollution.https://doi.org/10.1186/s42269-025-01319-1Paint industryEffluentBacillus cereusLaccase enzyme
spellingShingle B. A. Oyedeji
N. R. Oloye
S. O. Adebajo
M. O. Taiwo
B. T. Folarin
A. K. Akintokun
Optimization and production of laccase enzyme by Bacillus cereus isolated from effluent of paint producing industry
Bulletin of the National Research Centre
Paint industry
Effluent
Bacillus cereus
Laccase enzyme
title Optimization and production of laccase enzyme by Bacillus cereus isolated from effluent of paint producing industry
title_full Optimization and production of laccase enzyme by Bacillus cereus isolated from effluent of paint producing industry
title_fullStr Optimization and production of laccase enzyme by Bacillus cereus isolated from effluent of paint producing industry
title_full_unstemmed Optimization and production of laccase enzyme by Bacillus cereus isolated from effluent of paint producing industry
title_short Optimization and production of laccase enzyme by Bacillus cereus isolated from effluent of paint producing industry
title_sort optimization and production of laccase enzyme by bacillus cereus isolated from effluent of paint producing industry
topic Paint industry
Effluent
Bacillus cereus
Laccase enzyme
url https://doi.org/10.1186/s42269-025-01319-1
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