Metastasis of Ewing Sarcoma to the Pancreas: Case Report and Literature Review
Ewing sarcoma (ES) is a highly aggressive malignant bone cancer. ES is part of the Ewing sarcoma family of tumors (ESFT), which express characteristic t(11;22) translocation as well as higher levels of CD99. Given that metastasis and tumor burden are significant prognostic factors in patient’s respo...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Oncological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2020/7075048 |
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| _version_ | 1849472712249966592 |
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| author | Hyma Polimera Prashanth Moku Shady Piedra Abusharar Monali Vasekar Jayakrishna Chintanaboina |
| author_facet | Hyma Polimera Prashanth Moku Shady Piedra Abusharar Monali Vasekar Jayakrishna Chintanaboina |
| author_sort | Hyma Polimera |
| collection | DOAJ |
| description | Ewing sarcoma (ES) is a highly aggressive malignant bone cancer. ES is part of the Ewing sarcoma family of tumors (ESFT), which express characteristic t(11;22) translocation as well as higher levels of CD99. Given that metastasis and tumor burden are significant prognostic factors in patient’s response to treatment, prompt diagnosis is needed to effectively treat ESFT patients. However, the challenges in classifying and characterizing ESFT complicate effective management and treatment of ES. In this report, we present a rare case of ES metastasis to the pancreas. Upon review of the literature, we found 39 cases of ESFT involving the pancreas, but only 3 were metastatic to the pancreas while the remaining cases of ESFT primarily originated from the pancreas. Given the rarity of such metastasis, the positive outcome in our patient’s case may explain the importance of prompt diagnosis in order to initiate appropriate treatment. |
| format | Article |
| id | doaj-art-da9ae2f38e2d4987b3b531eb69048bc9 |
| institution | Kabale University |
| issn | 2090-6706 2090-6714 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Oncological Medicine |
| spelling | doaj-art-da9ae2f38e2d4987b3b531eb69048bc92025-08-20T03:24:26ZengWileyCase Reports in Oncological Medicine2090-67062090-67142020-01-01202010.1155/2020/70750487075048Metastasis of Ewing Sarcoma to the Pancreas: Case Report and Literature ReviewHyma Polimera0Prashanth Moku1Shady Piedra Abusharar2Monali Vasekar3Jayakrishna Chintanaboina4Penn State Hershey Medical Center, Hershey, Pennsylvania 17033, USAPenn State Hershey Medical Center, Hershey, Pennsylvania 17033, USAPenn State Hershey Medical Center, Hershey, Pennsylvania 17033, USAPenn State Hershey Medical Center, Hershey, Pennsylvania 17033, USAPenn State Hershey Medical Center, Hershey, Pennsylvania 17033, USAEwing sarcoma (ES) is a highly aggressive malignant bone cancer. ES is part of the Ewing sarcoma family of tumors (ESFT), which express characteristic t(11;22) translocation as well as higher levels of CD99. Given that metastasis and tumor burden are significant prognostic factors in patient’s response to treatment, prompt diagnosis is needed to effectively treat ESFT patients. However, the challenges in classifying and characterizing ESFT complicate effective management and treatment of ES. In this report, we present a rare case of ES metastasis to the pancreas. Upon review of the literature, we found 39 cases of ESFT involving the pancreas, but only 3 were metastatic to the pancreas while the remaining cases of ESFT primarily originated from the pancreas. Given the rarity of such metastasis, the positive outcome in our patient’s case may explain the importance of prompt diagnosis in order to initiate appropriate treatment.http://dx.doi.org/10.1155/2020/7075048 |
| spellingShingle | Hyma Polimera Prashanth Moku Shady Piedra Abusharar Monali Vasekar Jayakrishna Chintanaboina Metastasis of Ewing Sarcoma to the Pancreas: Case Report and Literature Review Case Reports in Oncological Medicine |
| title | Metastasis of Ewing Sarcoma to the Pancreas: Case Report and Literature Review |
| title_full | Metastasis of Ewing Sarcoma to the Pancreas: Case Report and Literature Review |
| title_fullStr | Metastasis of Ewing Sarcoma to the Pancreas: Case Report and Literature Review |
| title_full_unstemmed | Metastasis of Ewing Sarcoma to the Pancreas: Case Report and Literature Review |
| title_short | Metastasis of Ewing Sarcoma to the Pancreas: Case Report and Literature Review |
| title_sort | metastasis of ewing sarcoma to the pancreas case report and literature review |
| url | http://dx.doi.org/10.1155/2020/7075048 |
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