Selection of an appropriate fluorescent reference material to assess microplastic recovery in natural waters

Abstract Monitoring programs have been recently proposed to characterize the presence of microplastics (MPs) in source and treated drinking waters. Successful implementation of such programs will require the development of standardized sampling protocols that can address MP particles < 20 µm, rep...

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Main Authors: Noah A. D’Ascanio, Husein Almuhtaram, Robert C. Andrews
Format: Article
Language:English
Published: SpringerOpen 2025-04-01
Series:Microplastics and Nanoplastics
Subjects:
Online Access:https://doi.org/10.1186/s43591-025-00125-w
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author Noah A. D’Ascanio
Husein Almuhtaram
Robert C. Andrews
author_facet Noah A. D’Ascanio
Husein Almuhtaram
Robert C. Andrews
author_sort Noah A. D’Ascanio
collection DOAJ
description Abstract Monitoring programs have been recently proposed to characterize the presence of microplastics (MPs) in source and treated drinking waters. Successful implementation of such programs will require the development of standardized sampling protocols that can address MP particles < 20 µm, representing the most abundant sizes and relevance in terms of potential human health impacts. Validation of sampling methodologies typically involve spike and recovery trials (to serve as positive controls). To-date, no known methods have been proposed for the production of fluorescent reference materials that are representative of the shape and size distribution of environmental MPs (excluding tire and rubber particles). In this study, an optimal fluorescence reference suspension was developed for use in spike and recovery assessments of microplastic sampling methods when considering source and treated drinking waters. Aqueous particle suspensions were prepared using both commercially available microspheres and lab-prepared MP fragments, such that relative standard deviations (RSD) were calculated within size bins. Nile red-stained polyethylene terephthalate (PET) fragments were identified as an optimal reference material based on an RSD of 2.5% among replicate spikes. No change in fluorescence intensity was observed for Nile red-stained PET fragments following a process to remove extraneous (non-plastic) particles that incorporated a Fenton’s reagent and enzyme-based methodology. In addition, fluorescence intensity of Nile red-stained PET fragments in solution was observed to be stable over a four-month period. As such, it is anticipated that fluorescent PET fragments may be employed in future studies where assessment of microplastic recovery is desired.
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spelling doaj-art-da9aab8f3edf4897942bde4e96b6baf62025-08-20T02:05:46ZengSpringerOpenMicroplastics and Nanoplastics2662-49662025-04-015111210.1186/s43591-025-00125-wSelection of an appropriate fluorescent reference material to assess microplastic recovery in natural watersNoah A. D’Ascanio0Husein Almuhtaram1Robert C. Andrews2Department of Civil and Mineral Engineering, University of TorontoDepartment of Civil and Mineral Engineering, University of TorontoDepartment of Civil and Mineral Engineering, University of TorontoAbstract Monitoring programs have been recently proposed to characterize the presence of microplastics (MPs) in source and treated drinking waters. Successful implementation of such programs will require the development of standardized sampling protocols that can address MP particles < 20 µm, representing the most abundant sizes and relevance in terms of potential human health impacts. Validation of sampling methodologies typically involve spike and recovery trials (to serve as positive controls). To-date, no known methods have been proposed for the production of fluorescent reference materials that are representative of the shape and size distribution of environmental MPs (excluding tire and rubber particles). In this study, an optimal fluorescence reference suspension was developed for use in spike and recovery assessments of microplastic sampling methods when considering source and treated drinking waters. Aqueous particle suspensions were prepared using both commercially available microspheres and lab-prepared MP fragments, such that relative standard deviations (RSD) were calculated within size bins. Nile red-stained polyethylene terephthalate (PET) fragments were identified as an optimal reference material based on an RSD of 2.5% among replicate spikes. No change in fluorescence intensity was observed for Nile red-stained PET fragments following a process to remove extraneous (non-plastic) particles that incorporated a Fenton’s reagent and enzyme-based methodology. In addition, fluorescence intensity of Nile red-stained PET fragments in solution was observed to be stable over a four-month period. As such, it is anticipated that fluorescent PET fragments may be employed in future studies where assessment of microplastic recovery is desired.https://doi.org/10.1186/s43591-025-00125-wNile redPETFragmentSuspensionSpike and recovery
spellingShingle Noah A. D’Ascanio
Husein Almuhtaram
Robert C. Andrews
Selection of an appropriate fluorescent reference material to assess microplastic recovery in natural waters
Microplastics and Nanoplastics
Nile red
PET
Fragment
Suspension
Spike and recovery
title Selection of an appropriate fluorescent reference material to assess microplastic recovery in natural waters
title_full Selection of an appropriate fluorescent reference material to assess microplastic recovery in natural waters
title_fullStr Selection of an appropriate fluorescent reference material to assess microplastic recovery in natural waters
title_full_unstemmed Selection of an appropriate fluorescent reference material to assess microplastic recovery in natural waters
title_short Selection of an appropriate fluorescent reference material to assess microplastic recovery in natural waters
title_sort selection of an appropriate fluorescent reference material to assess microplastic recovery in natural waters
topic Nile red
PET
Fragment
Suspension
Spike and recovery
url https://doi.org/10.1186/s43591-025-00125-w
work_keys_str_mv AT noahadascanio selectionofanappropriatefluorescentreferencematerialtoassessmicroplasticrecoveryinnaturalwaters
AT huseinalmuhtaram selectionofanappropriatefluorescentreferencematerialtoassessmicroplasticrecoveryinnaturalwaters
AT robertcandrews selectionofanappropriatefluorescentreferencematerialtoassessmicroplasticrecoveryinnaturalwaters