Marine bioactives: Pioneering sustainable solutions for advanced cosmetics and therapeutics
Marine ecosystems harbor an extraordinary diversity of bioactive compounds with substantial potential in cosmetic and pharmaceutical applications. This review explores the applications of marine-derived bioactive compounds, including polysaccharides, peptides, lipids, and pigments, highlighting thei...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-08-01
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| Series: | Pharmacological Research |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1043661825002932 |
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| author | Fahrul Nurkolis |
| author_facet | Fahrul Nurkolis |
| author_sort | Fahrul Nurkolis |
| collection | DOAJ |
| description | Marine ecosystems harbor an extraordinary diversity of bioactive compounds with substantial potential in cosmetic and pharmaceutical applications. This review explores the applications of marine-derived bioactive compounds, including polysaccharides, peptides, lipids, and pigments, highlighting their significant therapeutic and cosmetic benefits such as antioxidant, anti-inflammatory, anticancer, skin-brightening, hydration, and anti-aging properties. Emphasizing the importance of sustainability, the review discusses innovative extraction methods, including enzyme-assisted and supercritical fluid extraction, to optimize yield and maintain bioactivity. Marine algae, invertebrates, and microorganisms represent key sources, each contributing unique compounds capable of addressing specific dermatological and systemic health needs. Regulatory challenges and sustainability concerns are critically examined to outline future directions for research and commercial development. Through interdisciplinary collaboration and advanced biotechnological approaches, marine cell culture achieves 50x higher yields than traditional extraction; synthetic biology sustainably produces rare compounds; advanced purification delivers 99.5 % pharmaceutical-grade purity; and life cycle assessments show 60 % lower environmental impact vs. terrestrial alternatives. |
| format | Article |
| id | doaj-art-da9899a8c32d4a3b9a81d37f8a25ea8a |
| institution | Kabale University |
| issn | 1096-1186 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Pharmacological Research |
| spelling | doaj-art-da9899a8c32d4a3b9a81d37f8a25ea8a2025-08-20T03:32:23ZengElsevierPharmacological Research1096-11862025-08-0121810786810.1016/j.phrs.2025.107868Marine bioactives: Pioneering sustainable solutions for advanced cosmetics and therapeuticsFahrul Nurkolis0Universitas Airlangga, Surabaya 60131, Indonesia; Medical Research Center of Indonesia, Surabaya 60281, Indonesia; State Islamic University of Sunan Kalijaga (UIN Sunan Kalijaga), Yogyakarta 55281, Indonesia; Corresponding author at: Universitas Airlangga, Surabaya 60131, Indonesia.Marine ecosystems harbor an extraordinary diversity of bioactive compounds with substantial potential in cosmetic and pharmaceutical applications. This review explores the applications of marine-derived bioactive compounds, including polysaccharides, peptides, lipids, and pigments, highlighting their significant therapeutic and cosmetic benefits such as antioxidant, anti-inflammatory, anticancer, skin-brightening, hydration, and anti-aging properties. Emphasizing the importance of sustainability, the review discusses innovative extraction methods, including enzyme-assisted and supercritical fluid extraction, to optimize yield and maintain bioactivity. Marine algae, invertebrates, and microorganisms represent key sources, each contributing unique compounds capable of addressing specific dermatological and systemic health needs. Regulatory challenges and sustainability concerns are critically examined to outline future directions for research and commercial development. Through interdisciplinary collaboration and advanced biotechnological approaches, marine cell culture achieves 50x higher yields than traditional extraction; synthetic biology sustainably produces rare compounds; advanced purification delivers 99.5 % pharmaceutical-grade purity; and life cycle assessments show 60 % lower environmental impact vs. terrestrial alternatives.http://www.sciencedirect.com/science/article/pii/S1043661825002932Marine bioactivesCosmetic applicationsPharmaceutical applicationsBioactive extractionAntioxidantAnti-inflammatory |
| spellingShingle | Fahrul Nurkolis Marine bioactives: Pioneering sustainable solutions for advanced cosmetics and therapeutics Pharmacological Research Marine bioactives Cosmetic applications Pharmaceutical applications Bioactive extraction Antioxidant Anti-inflammatory |
| title | Marine bioactives: Pioneering sustainable solutions for advanced cosmetics and therapeutics |
| title_full | Marine bioactives: Pioneering sustainable solutions for advanced cosmetics and therapeutics |
| title_fullStr | Marine bioactives: Pioneering sustainable solutions for advanced cosmetics and therapeutics |
| title_full_unstemmed | Marine bioactives: Pioneering sustainable solutions for advanced cosmetics and therapeutics |
| title_short | Marine bioactives: Pioneering sustainable solutions for advanced cosmetics and therapeutics |
| title_sort | marine bioactives pioneering sustainable solutions for advanced cosmetics and therapeutics |
| topic | Marine bioactives Cosmetic applications Pharmaceutical applications Bioactive extraction Antioxidant Anti-inflammatory |
| url | http://www.sciencedirect.com/science/article/pii/S1043661825002932 |
| work_keys_str_mv | AT fahrulnurkolis marinebioactivespioneeringsustainablesolutionsforadvancedcosmeticsandtherapeutics |