Cytokine Reduction in the Treatment of Joint Conditions
The destruction of joints caused by rheumatoid arthritis and osteoarthritis is characterized by an imbalance of enzyme catalysed cartilage breakdown and regeneration. A complex cytokine network perpetuates joint conditions by direct regulation of metalloproteases, by indirect recruitment of cells th...
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Main Authors: | J. D. Sipe, J. Martel-Pelletier, I. G. Otterness, J.-P. Pelletier |
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Format: | Article |
Language: | English |
Published: |
Wiley
1994-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/S0962935194000359 |
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