Machine learning tools for deciphering the regulatory logic of enhancers in health and disease

Transcriptional enhancers are DNA regulatory elements that control the levels and spatiotemporal patterns of gene expression during development, homeostasis, and pathophysiological processes. Enhancer identification and characterization at the genome-wide scale rely on their structural characteristi...

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Bibliographic Details
Main Authors: Spyros Foutadakis, Vasiliki Bourika, Ioanna Styliara, Panagiotis Koufargyris, Asimina Safarika, Eleni Karakike
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Genetics
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Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2025.1603687/full
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