Publication of data sharing statements in clinical trials by cardiovascular journals: a quantitative and qualitative analysis

Abstract Many cardiovascular disease (CVD) journals request data sharing statements upon trial report submission, but their compliance in publishing these statements remains unclear. We therefore performed a quantitative analysis to evaluate the current practice of the publications of data sharing s...

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Main Authors: Yingxin Liu, Gregory Y. H. Lip, Jingyi Zhang, Xuerui Bai, Jianfeng Li, Lehana Thabane, Harriette G. C. Van Spall, Guowei Li
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Data
Online Access:https://doi.org/10.1038/s41597-025-05510-x
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author Yingxin Liu
Gregory Y. H. Lip
Jingyi Zhang
Xuerui Bai
Jianfeng Li
Lehana Thabane
Harriette G. C. Van Spall
Guowei Li
author_facet Yingxin Liu
Gregory Y. H. Lip
Jingyi Zhang
Xuerui Bai
Jianfeng Li
Lehana Thabane
Harriette G. C. Van Spall
Guowei Li
author_sort Yingxin Liu
collection DOAJ
description Abstract Many cardiovascular disease (CVD) journals request data sharing statements upon trial report submission, but their compliance in publishing these statements remains unclear. We therefore performed a quantitative analysis to evaluate the current practice of the publications of data sharing statements in clinical trials by CVD journals, which included 78 CVD journals that published clinical trials from Jan 2019 to Dec 2022 and had data sharing statement request. Multivariable logistic regression analysis was used to examine the association between journal characteristics and journals’ publications of statements. We also ran an online qualitative survey by sending anonymous questionnaires to editors-in-chief from CVD journals for their opinions on journals’ publications of statements, trying to further explore why the journals did not publish statements. Their perspectives could provide in-depth information on and new insights into promoting publications of data sharing statements. This quantitative and qualitative analysis assessing the current practice of publishing data sharing statements by CVD journals, may generate new evidence to promote the actual data sharing and transparency in CVD trials.
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spelling doaj-art-da92fcc896a641e9b3c3c2cdfb8a064d2025-08-20T03:45:45ZengNature PortfolioScientific Data2052-44632025-07-0112111010.1038/s41597-025-05510-xPublication of data sharing statements in clinical trials by cardiovascular journals: a quantitative and qualitative analysisYingxin Liu0Gregory Y. H. Lip1Jingyi Zhang2Xuerui Bai3Jianfeng Li4Lehana Thabane5Harriette G. C. Van Spall6Guowei Li7Center for Clinical Epidemiology and Methodology (CCEM), The Affiliated Guangdong Second Provincial General Hospital of Jinan UniversityLiverpool Centre for Cardiovascular Sciences at University of Liverpool, Liverpool John Moores University, Liverpool Heart & Chest HospitalCenter for Clinical Epidemiology and Methodology (CCEM), The Affiliated Guangdong Second Provincial General Hospital of Jinan UniversityDepartment of Epidemiology, School of Medicine, Jinan UniversityDepartment of Epidemiology and Health Statistics, School of Public Health, Guangdong Medical UniversityDepartment of Health Research Methods, Evidence, and Impact (HEI), McMaster UniversityDepartment of Health Research Methods, Evidence, and Impact (HEI), McMaster UniversityCenter for Clinical Epidemiology and Methodology (CCEM), The Affiliated Guangdong Second Provincial General Hospital of Jinan UniversityAbstract Many cardiovascular disease (CVD) journals request data sharing statements upon trial report submission, but their compliance in publishing these statements remains unclear. We therefore performed a quantitative analysis to evaluate the current practice of the publications of data sharing statements in clinical trials by CVD journals, which included 78 CVD journals that published clinical trials from Jan 2019 to Dec 2022 and had data sharing statement request. Multivariable logistic regression analysis was used to examine the association between journal characteristics and journals’ publications of statements. We also ran an online qualitative survey by sending anonymous questionnaires to editors-in-chief from CVD journals for their opinions on journals’ publications of statements, trying to further explore why the journals did not publish statements. Their perspectives could provide in-depth information on and new insights into promoting publications of data sharing statements. This quantitative and qualitative analysis assessing the current practice of publishing data sharing statements by CVD journals, may generate new evidence to promote the actual data sharing and transparency in CVD trials.https://doi.org/10.1038/s41597-025-05510-x
spellingShingle Yingxin Liu
Gregory Y. H. Lip
Jingyi Zhang
Xuerui Bai
Jianfeng Li
Lehana Thabane
Harriette G. C. Van Spall
Guowei Li
Publication of data sharing statements in clinical trials by cardiovascular journals: a quantitative and qualitative analysis
Scientific Data
title Publication of data sharing statements in clinical trials by cardiovascular journals: a quantitative and qualitative analysis
title_full Publication of data sharing statements in clinical trials by cardiovascular journals: a quantitative and qualitative analysis
title_fullStr Publication of data sharing statements in clinical trials by cardiovascular journals: a quantitative and qualitative analysis
title_full_unstemmed Publication of data sharing statements in clinical trials by cardiovascular journals: a quantitative and qualitative analysis
title_short Publication of data sharing statements in clinical trials by cardiovascular journals: a quantitative and qualitative analysis
title_sort publication of data sharing statements in clinical trials by cardiovascular journals a quantitative and qualitative analysis
url https://doi.org/10.1038/s41597-025-05510-x
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