Role of lactate dehydrogenase A in malignant hematological diseases

Role of lactate dehydrogenase A in malignant hematological diseases

Lactate dehydrogenase A (LDHA) is an important enzyme involved in the anaerobic glycolysis of cells, catalyzing the conversion of pyruvate to lactate and participating in processes such as tumor proliferation, migration, invasion, and the regulation of the tumor microenvironment. High expression lev...

Full description

Saved in:

Bibliographic Details
Main Author:	MO Yuzhen, CHEN Tingting, ZHOU Hebing
Format:	Article
Language:	zho
Published:	Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2025-07-01
Series:	Jichu yixue yu linchuang
Subjects:	lactate dehydrogenase a\|malignant hematological disease\|glycolysis
Online Access:	https://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2025-45-7-958.pdf
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Role of lactate dehydrogenase A in the regulation of podocyte metabolism and glucose uptake under hyperglycemic conditions
by: Audzeyenka Irena, et al.
Published: (2025-04-01)

A paternal lactate dehydrogenase critically enhances male gametogenesis and malaria transmission
by: Annie Z. Tremp, et al.
Published: (2025-07-01)

Lactate dehydrogenase A-coupled NAD+ regeneration is critical for acute myeloid leukemia cell survival
by: Ayşegül Erdem, et al.
Published: (2025-05-01)

Association between the lactate dehydrogenase-to-albumin ratio and 28-day mortality in septic patients with malignancies: analysis of the MIMIC-IV database
by: Yongshi Shen, et al.
Published: (2025-04-01)

Lactate dehydrogenase is the Achilles’ heel of Lyme disease bacterium Borreliella burgdorferi
by: Ching Wooen Sze, et al.
Published: (2025-04-01)

PURIFICATION OF LACTATE DEHYDROGENASE-C4 FROM SEMINAL PLASMA OF MALE INFERTILITY
by: Shihab A. Al-Bajari, et al.
Published: (2018-11-01)

The role of non-malignant B cells in malignant hematologic diseases
by: Daquan Gao
Published: (2025-12-01)

The prognostic value of lactate dehydrogenase/albumin ratio in extranodal natural killer/T cell lymphoma
by: Na Li, et al.
Published: (2025-07-01)

Prognostic value of lactate dehydrogenase, serum albumin and the lactate dehydrogenase/albumin ratio in patients with diffuse large B-cell lymphoma
by: Wenke Wu, et al.
Published: (2024-12-01)

Association between lactate dehydrogenase to albumin ratio and ICU mortality in patients with acute kidney injury: a retrospective cohort study
by: Jianting Gao, et al.
Published: (2025-06-01)

Lactate-Dehydrogenase-5 May Play a Key Role in the Disturbance of Brain Energy Caused by Tuberculous Meningitis
by: Qingdong Zhu, et al.
Published: (2025-04-01)

Serum lactate dehydrogenase level in preeclampsia and its correlation with disease severity, maternal and perinatal outcomes
by: Sallama Kamel Nasir, et al.
Published: (2025-03-01)

Nuclear Lactate Dehydrogenase A Resists Cardiomyocyte Cell Cycle Arrest Induced by Oxidative Stress
by: Mengfei Cao, et al.
Published: (2025-07-01)

Dual role of lactate in human health and disease
by: Sudhir Kumar, et al.
Published: (2025-08-01)

Human D‐Lactate Dehydrogenase Deficiency: A Case Report in a Young Boy
by: T. B. Sloth, et al.
Published: (2025-07-01)

Transcriptional regulation of lactate dehydrogenase activity in rat kidney cells in diabetic nephropathy
by: A. T. Eprintsev, et al.
Published: (2024-04-01)

The effect of lactate dehydrogenase B and its mediated histone lactylation on chondrocyte ferroptosis during osteoarthritis
by: Yang Zhang, et al.
Published: (2025-05-01)

Using lactate dehydrogenase to predict the severity of respiratory distress in term newborn infants with no perinatal asphyxia
by: Miran Lee, et al.
Published: (2021-06-01)

Lactate dehydrogenase to albumin ratio as an independent factor for 28-day mortality of neonatal sepsis
by: Xiaohong Xia, et al.
Published: (2025-04-01)

Diagnostic Accuracy of Lactate Dehydrogenase and Serum Creatine Kinase to Detect Prenatal Hypoxia in Term Neonates
by: Sabahat Fatima, et al.
Published: (2025-04-01)

Lactate dehydrogenase to albumin ratio and poor prognosis after thrombolysis in ischemic stroke patients: developing a novel nomogram
by: Xiao-Dan Zhang, et al.
Published: (2025-04-01)

The role of lactate dehydrogenase (LDH) and vascular endothelial growth factor (VEGF) in nasopharyngeal cancer: a literature review
by: Mochammad Alfian Sulaksana, et al.
Published: (2025-08-01)

Lactate dehydrogenases promote glioblastoma growth and invasion via a metabolic symbiosis
by: Joris Guyon, et al.
Published: (2022-10-01)

Conformational features of lactate dehydrogenase: temperature effect in presence of small molecules, mathematical model
by: F. N. Gilmiyarova, et al.
Published: (2020-10-01)

Effect of lactate dehydrogenase A on osteoclasts during alveolar bone remodeling after mandibular ramus osteotomy
by: ZHENG Yushan, et al.
Published: (2025-08-01)

Lactate dehydrogenase A: a potential new target for tumor drug resistance intervention
by: Mingyue Wang, et al.
Published: (2025-07-01)

The spectrum of lactate dehydrogenase isozymes in ovarian tissue of cows under different physiological states and pathologies
by: M. M. Akymyshyn, et al.
Published: (2024-09-01)

Specific Activity of Lactate Dehydrogenase in Muscle and Liver Tissues of Rats Exposed to Intermittent Hypobaric Hypoxia
by: Syarifah Dewi, et al.
Published: (2025-01-01)

Secondary infections after cytotoxic chemotherapy in patient with hematological malignancies
by: Seyit Ali Büyüktuna, et al.
Published: (2017-07-01)

Unraveling Burden of Isocitrate Dehydrogenase Mutations in AcuteMyeloid Leukemia; Clinico-Hematological Correlation and PrognosticRelevance
by: Syeda Hina Abbas, et al.
Published: (2025-05-01)

Association between lactate dehydrogenase levels and oncologic outcomes in metastatic prostate cancer: A meta‐analysis
by: Fan Li, et al.
Published: (2020-10-01)

Impact of the muscular Training on the levels of Sodium and Potassium and on the activity of lactate dehydrogenase in blood serum
by: Zina Lafta Hassan, et al.
Published: (2023-01-01)

Prognostic value of the lactate dehydrogenase to albumin ratio in cancer patients
by: Dongqi Chai, et al.
Published: (2025-07-01)

The importance of determining lactate dehydrogenase in laboratory and experimental work in oncology
by: Jurišić Vladimir, et al.
Published: (2024-01-01)

Prognostic Significance of Thymidine Kinase-1 versus β2-Microglobulin and Lactate Dehydrogenase in Lymphoproliferative Diseases
by: N.K. Parilova, et al.
Published: (2016-01-01)

Synthesis, characterization and Molecular docking simulation of novel Atorvastatin Aspirin ester, and study activation effect on lactate dehydrogenase enzyme in atherosclerosis patient
by: Asmaa Ghazi Shukr Al-ajeely, et al.
Published: (2025-08-01)

Factors influencing salivary lactate dehydrogenase levels in oral squamous cell carcinoma and oral potentially malignant disorders
by: Rosa María López-Pintor, et al.
Published: (2025-01-01)

The effect of vitamin E and A supplementation on some hematological parameters and lactate levels of elite taekwondo players
by: Alpaslan Gorucu
Published: (2017-04-01)

U-shaped association of serum lactate dehydrogenase with all-cause mortality in cancer patients: a retrospective cohort study
by: Mao Zhang, et al.
Published: (2025-07-01)

Correlation of serum lactate dehydrogenase (LDH) level with feto-maternal outcome in normal pregnancy and preeclamptic disorders
by: Rupali Modak, et al.
Published: (2024-05-01)