Coexistence of Hodgkin’s Lymphoma and Castleman’s Disease: A Case Report with Successful Response to Chemotherapy and Radiotherapy
Background. Castleman’s disease is a rare clinicopathological entity of unknown origin. Coexistence of Hodgkin’s lymphoma and Castleman’s disease is rare. We report a case of Hodgkin’s disease of cervical lymph nodes in a patient previously diagnosed with Castleman’s disease. Case Presentation. A 43...
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| Format: | Article |
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Wiley
2013-01-01
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| Series: | Case Reports in Oncological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2013/487205 |
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| author | Amina Mohtaram Mohammed Afif Tanae Sghiri Amal Rami Rachida Latib Fouad Kettani Meryam Ben Ameur El Youbi Saber Boutayeb Tayeb Kebdani Noureddine Benjaafar Imane Aaribi Hassan Errihani |
| author_facet | Amina Mohtaram Mohammed Afif Tanae Sghiri Amal Rami Rachida Latib Fouad Kettani Meryam Ben Ameur El Youbi Saber Boutayeb Tayeb Kebdani Noureddine Benjaafar Imane Aaribi Hassan Errihani |
| author_sort | Amina Mohtaram |
| collection | DOAJ |
| description | Background. Castleman’s disease is a rare clinicopathological entity of unknown origin. Coexistence of Hodgkin’s lymphoma and Castleman’s disease is rare. We report a case of Hodgkin’s disease of cervical lymph nodes in a patient previously diagnosed with Castleman’s disease. Case Presentation. A 43-year-old man admitted in July 2009 for a right cervical pain with lymph node at the physician examination. He underwent a right adenectomy and histological studies showed typical features of Castleman’s disease. Three years after, the patient consulted for increasing the volume of cervical lymph node. Clinical examination showed a right cervical lymph node of 3 cm. The computed tomography scan of chest, abdominal and pelvic was normal. Histological and immunohistochemical studies of cervical lymph node biopsy specimen were in favor of Castleman’s disease associated with Hodgkin’s disease. Reed-Sternberg cells were positive for CD15 and CD30. The patient received chemotherapy based on anthracyclines, bleomycin, vinblastine, and dacarbazine (ABVD) and radiotherapy with complete response. Conclusion. Prevalence of Hodgkin’s lymphoma in Castleman’s disease is more difficult to establish because of the low number of cases reported in the literature. |
| format | Article |
| id | doaj-art-da8d53e0d8b644549430dec649150667 |
| institution | Kabale University |
| issn | 2090-6706 2090-6714 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Oncological Medicine |
| spelling | doaj-art-da8d53e0d8b644549430dec6491506672025-02-03T07:24:38ZengWileyCase Reports in Oncological Medicine2090-67062090-67142013-01-01201310.1155/2013/487205487205Coexistence of Hodgkin’s Lymphoma and Castleman’s Disease: A Case Report with Successful Response to Chemotherapy and RadiotherapyAmina Mohtaram0Mohammed Afif1Tanae Sghiri2Amal Rami3Rachida Latib4Fouad Kettani5Meryam Ben Ameur El Youbi6Saber Boutayeb7Tayeb Kebdani8Noureddine Benjaafar9Imane Aaribi10Hassan Errihani11Department of Medical Oncology, National Institute of Oncology, Rabat, MoroccoDepartment of Radiotherapy, National Institute of Oncology, Rabat, MoroccoDepartment of Medical Oncology, National Institute of Oncology, Rabat, MoroccoDepartment of Radiology, National Institute of Oncology, Rabat, MoroccoDepartment of Radiology, National Institute of Oncology, Rabat, MoroccoCenter of Pathology United Nations, Rabat, MoroccoDepartment of Medical Oncology, National Institute of Oncology, Rabat, MoroccoDepartment of Medical Oncology, National Institute of Oncology, Rabat, MoroccoDepartment of Radiotherapy, National Institute of Oncology, Rabat, MoroccoDepartment of Radiotherapy, National Institute of Oncology, Rabat, MoroccoDepartment of Medical Oncology, National Institute of Oncology, Rabat, MoroccoDepartment of Medical Oncology, National Institute of Oncology, Rabat, MoroccoBackground. Castleman’s disease is a rare clinicopathological entity of unknown origin. Coexistence of Hodgkin’s lymphoma and Castleman’s disease is rare. We report a case of Hodgkin’s disease of cervical lymph nodes in a patient previously diagnosed with Castleman’s disease. Case Presentation. A 43-year-old man admitted in July 2009 for a right cervical pain with lymph node at the physician examination. He underwent a right adenectomy and histological studies showed typical features of Castleman’s disease. Three years after, the patient consulted for increasing the volume of cervical lymph node. Clinical examination showed a right cervical lymph node of 3 cm. The computed tomography scan of chest, abdominal and pelvic was normal. Histological and immunohistochemical studies of cervical lymph node biopsy specimen were in favor of Castleman’s disease associated with Hodgkin’s disease. Reed-Sternberg cells were positive for CD15 and CD30. The patient received chemotherapy based on anthracyclines, bleomycin, vinblastine, and dacarbazine (ABVD) and radiotherapy with complete response. Conclusion. Prevalence of Hodgkin’s lymphoma in Castleman’s disease is more difficult to establish because of the low number of cases reported in the literature.http://dx.doi.org/10.1155/2013/487205 |
| spellingShingle | Amina Mohtaram Mohammed Afif Tanae Sghiri Amal Rami Rachida Latib Fouad Kettani Meryam Ben Ameur El Youbi Saber Boutayeb Tayeb Kebdani Noureddine Benjaafar Imane Aaribi Hassan Errihani Coexistence of Hodgkin’s Lymphoma and Castleman’s Disease: A Case Report with Successful Response to Chemotherapy and Radiotherapy Case Reports in Oncological Medicine |
| title | Coexistence of Hodgkin’s Lymphoma and Castleman’s Disease: A Case Report with Successful Response to Chemotherapy and Radiotherapy |
| title_full | Coexistence of Hodgkin’s Lymphoma and Castleman’s Disease: A Case Report with Successful Response to Chemotherapy and Radiotherapy |
| title_fullStr | Coexistence of Hodgkin’s Lymphoma and Castleman’s Disease: A Case Report with Successful Response to Chemotherapy and Radiotherapy |
| title_full_unstemmed | Coexistence of Hodgkin’s Lymphoma and Castleman’s Disease: A Case Report with Successful Response to Chemotherapy and Radiotherapy |
| title_short | Coexistence of Hodgkin’s Lymphoma and Castleman’s Disease: A Case Report with Successful Response to Chemotherapy and Radiotherapy |
| title_sort | coexistence of hodgkin s lymphoma and castleman s disease a case report with successful response to chemotherapy and radiotherapy |
| url | http://dx.doi.org/10.1155/2013/487205 |
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