LiaS gene from two-component system is essential for caries pathogenicity in dual-species biofilms of Streptococcus mutans and Candida albicans

LiaS gene from two-component system is essential for caries pathogenicity in dual-species biofilms of Streptococcus mutans and Candida albicans

IntroductionThis study elucidated the critical role of the liaS gene in the Streptococcus mutans (S. mutans) two-component signal (TCS) transduction system during cross-kingdom interactions with Candida albicans (C. albicans). This gene governs the cariogenic potential of dual-species biofilms.Metho...

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Bibliographic Details
Main Authors: Yanfan Cao, Yu Zeng, Yuze Yang, Guowu Gan, Shuai Chen, Xiaojing Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Microbiology
Subjects:
Streptococcus mutans
Candida albicans
liaS
two-component system
biofilm
extracellular polysaccharide
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1612841/full
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