Prevalence of Anti-Thyroid Peroxidase Antibody positivity and its Effect on Pregnancy Outcome in women with Unexplained infertility

Introduction:Thyroid disease is the second endocrine disorder that affects women in reproductive age and its autoimmunity can affect the outcome of the pregnancy. The aim of this study was to investigate the prevalence of Anti-TPO positivity and its effect on pregnancy outcomes in women with unexpla...

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Main Authors: Faranak Jalilvand, Shahla Farzipour, Firouz Amani, Jinous Gamisi
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2023-07-01
Series:Patient Safety and Quality Improvement Journal
Subjects:
Online Access:https://psj.mums.ac.ir/article_23297_21183235046dfc4849ffe4334fa2da40.pdf
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author Faranak Jalilvand
Shahla Farzipour
Firouz Amani
Jinous Gamisi
author_facet Faranak Jalilvand
Shahla Farzipour
Firouz Amani
Jinous Gamisi
author_sort Faranak Jalilvand
collection DOAJ
description Introduction:Thyroid disease is the second endocrine disorder that affects women in reproductive age and its autoimmunity can affect the outcome of the pregnancy. The aim of this study was to investigate the prevalence of Anti-TPO positivity and its effect on pregnancy outcomes in women with unexplained infertility. Materials and Methods: In this cross-sectional descriptive study, 93 infertile women who referred to infertility center at Ardabil city during 2020-2021 were recruited for the study. Information such as age, BMI, TSH, prolactin and results of Anti-TPO were completed for all cases and then analyzed by statistical methods in SPSS version 23.  Results: The prevalence of anti-TPO positivity was 73.1% (n=68). The mean of BMI, Age, TSH and prolactin were not significantly different in women with Anti-TPO positivity as compared to others. There was no relation between TSH and Anti-TPO results and Also between TSH and results of pregnancy. Conclusion:Our results indicate that anti-TPO screening in pregnancy, may aid in early identification of the women at risk at the future.
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spelling doaj-art-da7c000471c241e7bc11d9948e2d39d42025-08-20T02:46:00ZengMashhad University of Medical SciencesPatient Safety and Quality Improvement Journal2345-44822345-44902023-07-0111318318810.22038/psj.2023.72661.139223297Prevalence of Anti-Thyroid Peroxidase Antibody positivity and its Effect on Pregnancy Outcome in women with Unexplained infertilityFaranak Jalilvand0Shahla Farzipour1Firouz Amani2Jinous Gamisi3Department of Obstetrics and Gynecology, School of medicine, Ardabil University of Medical Sciences, Ardabil, Iran.Department of Obstetrics and Gynecology, School of medicine, Ardabil University of Medical Sciences, Ardabil, Iran.Department of Community Medicine, School of medicine, Ardabil University of Medical Sciences, Ardabil, Iran.Department of Obstetrics and Gynecology, School of medicine, Ardabil University of Medical Sciences, Ardabil, Iran.Introduction:Thyroid disease is the second endocrine disorder that affects women in reproductive age and its autoimmunity can affect the outcome of the pregnancy. The aim of this study was to investigate the prevalence of Anti-TPO positivity and its effect on pregnancy outcomes in women with unexplained infertility. Materials and Methods: In this cross-sectional descriptive study, 93 infertile women who referred to infertility center at Ardabil city during 2020-2021 were recruited for the study. Information such as age, BMI, TSH, prolactin and results of Anti-TPO were completed for all cases and then analyzed by statistical methods in SPSS version 23.  Results: The prevalence of anti-TPO positivity was 73.1% (n=68). The mean of BMI, Age, TSH and prolactin were not significantly different in women with Anti-TPO positivity as compared to others. There was no relation between TSH and Anti-TPO results and Also between TSH and results of pregnancy. Conclusion:Our results indicate that anti-TPO screening in pregnancy, may aid in early identification of the women at risk at the future.https://psj.mums.ac.ir/article_23297_21183235046dfc4849ffe4334fa2da40.pdfeuthyroidpregnancy outcomeanti-tpo
spellingShingle Faranak Jalilvand
Shahla Farzipour
Firouz Amani
Jinous Gamisi
Prevalence of Anti-Thyroid Peroxidase Antibody positivity and its Effect on Pregnancy Outcome in women with Unexplained infertility
Patient Safety and Quality Improvement Journal
euthyroid
pregnancy outcome
anti-tpo
title Prevalence of Anti-Thyroid Peroxidase Antibody positivity and its Effect on Pregnancy Outcome in women with Unexplained infertility
title_full Prevalence of Anti-Thyroid Peroxidase Antibody positivity and its Effect on Pregnancy Outcome in women with Unexplained infertility
title_fullStr Prevalence of Anti-Thyroid Peroxidase Antibody positivity and its Effect on Pregnancy Outcome in women with Unexplained infertility
title_full_unstemmed Prevalence of Anti-Thyroid Peroxidase Antibody positivity and its Effect on Pregnancy Outcome in women with Unexplained infertility
title_short Prevalence of Anti-Thyroid Peroxidase Antibody positivity and its Effect on Pregnancy Outcome in women with Unexplained infertility
title_sort prevalence of anti thyroid peroxidase antibody positivity and its effect on pregnancy outcome in women with unexplained infertility
topic euthyroid
pregnancy outcome
anti-tpo
url https://psj.mums.ac.ir/article_23297_21183235046dfc4849ffe4334fa2da40.pdf
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AT firouzamani prevalenceofantithyroidperoxidaseantibodypositivityanditseffectonpregnancyoutcomeinwomenwithunexplainedinfertility
AT jinousgamisi prevalenceofantithyroidperoxidaseantibodypositivityanditseffectonpregnancyoutcomeinwomenwithunexplainedinfertility