Histopathological Characteristics of Cutaneous Melanoma in Isfahan, Iran, from 2013 to 2018
Objectives. To investigate the histopathological characteristics of cutaneous melanoma in Isfahan from 2013 to 2018, according to histopathological subtype, lesions location, Clark level, and Breslow thickness. Methods. A descriptive, retrospective study in reports of Alzahra Hospital and Dr. Rajabi...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Journal of Skin Cancer |
| Online Access: | http://dx.doi.org/10.1155/2022/4490648 |
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| _version_ | 1850166480883154944 |
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| author | Zahra Malakoutikhah Fatemeh Mohaghegh Siavash Karimi Parvin Rajabi Elham T. Tabatabaei |
| author_facet | Zahra Malakoutikhah Fatemeh Mohaghegh Siavash Karimi Parvin Rajabi Elham T. Tabatabaei |
| author_sort | Zahra Malakoutikhah |
| collection | DOAJ |
| description | Objectives. To investigate the histopathological characteristics of cutaneous melanoma in Isfahan from 2013 to 2018, according to histopathological subtype, lesions location, Clark level, and Breslow thickness. Methods. A descriptive, retrospective study in reports of Alzahra Hospital and Dr. Rajabi Pathology Laboratory in Isfahan. Results. In total, 45 patients were included in this study. The most prevalent histopathological subtype was acral lentiginous melanoma (48.89%), followed by lentigo maligna melanoma (17.78%), nodular melanoma (11.11%), and superficial spreading melanoma (8.89%). Most malignant lesions were on the foot and toes (31.1%) and face (24.4%). Tumor invasion level was mainly at Clark level IV (42.2%). Furthermore, the mean depth of tumor penetration (Breslow thickness) was 3.87 ± 3.35. Conclusions. Our study revealed the characteristics of melanoma in the Iranian population. Our results showed a similar trend with previous studies in the Asian population. Further investigations are needed to elucidate the role of ethnic and environmental risk factors for developing melanoma in different populations. |
| format | Article |
| id | doaj-art-da79ceb94085444fa9286ac57e677049 |
| institution | OA Journals |
| issn | 2090-2913 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Skin Cancer |
| spelling | doaj-art-da79ceb94085444fa9286ac57e6770492025-08-20T02:21:25ZengWileyJournal of Skin Cancer2090-29132022-01-01202210.1155/2022/4490648Histopathological Characteristics of Cutaneous Melanoma in Isfahan, Iran, from 2013 to 2018Zahra Malakoutikhah0Fatemeh Mohaghegh1Siavash Karimi2Parvin Rajabi3Elham T. Tabatabaei4Applied Physiology Research CenterDepartment of DermatologySchool of MedicineDepartment of PathologyDepartment of DermatologyObjectives. To investigate the histopathological characteristics of cutaneous melanoma in Isfahan from 2013 to 2018, according to histopathological subtype, lesions location, Clark level, and Breslow thickness. Methods. A descriptive, retrospective study in reports of Alzahra Hospital and Dr. Rajabi Pathology Laboratory in Isfahan. Results. In total, 45 patients were included in this study. The most prevalent histopathological subtype was acral lentiginous melanoma (48.89%), followed by lentigo maligna melanoma (17.78%), nodular melanoma (11.11%), and superficial spreading melanoma (8.89%). Most malignant lesions were on the foot and toes (31.1%) and face (24.4%). Tumor invasion level was mainly at Clark level IV (42.2%). Furthermore, the mean depth of tumor penetration (Breslow thickness) was 3.87 ± 3.35. Conclusions. Our study revealed the characteristics of melanoma in the Iranian population. Our results showed a similar trend with previous studies in the Asian population. Further investigations are needed to elucidate the role of ethnic and environmental risk factors for developing melanoma in different populations.http://dx.doi.org/10.1155/2022/4490648 |
| spellingShingle | Zahra Malakoutikhah Fatemeh Mohaghegh Siavash Karimi Parvin Rajabi Elham T. Tabatabaei Histopathological Characteristics of Cutaneous Melanoma in Isfahan, Iran, from 2013 to 2018 Journal of Skin Cancer |
| title | Histopathological Characteristics of Cutaneous Melanoma in Isfahan, Iran, from 2013 to 2018 |
| title_full | Histopathological Characteristics of Cutaneous Melanoma in Isfahan, Iran, from 2013 to 2018 |
| title_fullStr | Histopathological Characteristics of Cutaneous Melanoma in Isfahan, Iran, from 2013 to 2018 |
| title_full_unstemmed | Histopathological Characteristics of Cutaneous Melanoma in Isfahan, Iran, from 2013 to 2018 |
| title_short | Histopathological Characteristics of Cutaneous Melanoma in Isfahan, Iran, from 2013 to 2018 |
| title_sort | histopathological characteristics of cutaneous melanoma in isfahan iran from 2013 to 2018 |
| url | http://dx.doi.org/10.1155/2022/4490648 |
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