A case of sepsis with multi-organ failure from a community-acquired Acinetobacter junii bacteremia in an immunocompetent patient
BACKGROUND: The Acinetobacter (A.) genus is a group of Gram-negative bacilli which mainly cause nosocomial infections or infections in immunocompromised patients. A. baumannii is the most common agent of human infection, and A. junii represents less than 3% of isolates. We present a rare case of A....
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Verduci Editore
2024-04-01
|
| Series: | Infectious Diseases and Tropical Medicine |
| Subjects: | |
| Online Access: | https://www.infectiousjournal.com/wp-content/uploads/sites/6/2024/04/e1385-1.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850272597529329664 |
|---|---|
| author | F. Bartilotti Matos M. Ribeirinha A. Salgado A. Pereira Guedes C. Figueiredo |
| author_facet | F. Bartilotti Matos M. Ribeirinha A. Salgado A. Pereira Guedes C. Figueiredo |
| author_sort | F. Bartilotti Matos |
| collection | DOAJ |
| description | BACKGROUND: The Acinetobacter (A.) genus is a group of Gram-negative bacilli which mainly cause nosocomial infections or infections in immunocompromised patients. A. baumannii is the most common agent of human infection, and A. junii represents less than 3% of isolates. We present a rare case of A. junii bacteremia and pneumonia in an immunocompetent patient with no recent hospital admissions or antibiotic exposure.
CASE PRESENTATION: We report the case of a 78-year-old man with a three-day history of shortness of breath, dry cough, and fever. Initial blood tests revealed leukocytosis and a raised C-reactive protein, while lung imaging showed right upper lobe consolidation. He was diagnosed with community-acquired pneumonia, rapidly evolving into respiratory failure and septic shock, necessitating mechanical invasive ventilation, vasopressor, and inotropic support. Blood cultures and cultures of tracheal aspirate were positive for A. junii. After the microbiology sensitivities were known, antibiotic therapy was changed to meropenem, resulting in a good clinical outcome and resolution of infection.
CONCLUSIONS: While A. junii is commonly a sensitive organism, there are reports of colistin and carbapenem resistance. It is important to document new presentations to expand our knowledge of this rare microorganism. |
| format | Article |
| id | doaj-art-da759eb8fb644b9da0cac35bffb25205 |
| institution | OA Journals |
| issn | 2379-4054 |
| language | English |
| publishDate | 2024-04-01 |
| publisher | Verduci Editore |
| record_format | Article |
| series | Infectious Diseases and Tropical Medicine |
| spelling | doaj-art-da759eb8fb644b9da0cac35bffb252052025-08-20T01:51:45ZengVerduci EditoreInfectious Diseases and Tropical Medicine2379-40542024-04-011010.32113/idtm_20244_13851385A case of sepsis with multi-organ failure from a community-acquired Acinetobacter junii bacteremia in an immunocompetent patientF. Bartilotti Matos0M. Ribeirinha1A. Salgado2A. Pereira Guedes3C. Figueiredo41Serviço de Doenças Infecciosas, Centro Hospitalar Vila Nova de Gaia, Espinho, PortugalServiço de Patologia Clínica, Centro Hospitalar Vila Nova de Gaia, Espinho, PortugalServiço de Medicina Intensiva Polivalente, Centro Hospitalar Vila Nova de Gaia, Espinho, PortugalServiço de Medicina Interna, Centro Hospitalar Vila Nova de Gaia, Espinho, PortugalServiço de Doenças Infecciosas, Centro Hospitalar Vila Nova de Gaia, Espinho, PortugalBACKGROUND: The Acinetobacter (A.) genus is a group of Gram-negative bacilli which mainly cause nosocomial infections or infections in immunocompromised patients. A. baumannii is the most common agent of human infection, and A. junii represents less than 3% of isolates. We present a rare case of A. junii bacteremia and pneumonia in an immunocompetent patient with no recent hospital admissions or antibiotic exposure. CASE PRESENTATION: We report the case of a 78-year-old man with a three-day history of shortness of breath, dry cough, and fever. Initial blood tests revealed leukocytosis and a raised C-reactive protein, while lung imaging showed right upper lobe consolidation. He was diagnosed with community-acquired pneumonia, rapidly evolving into respiratory failure and septic shock, necessitating mechanical invasive ventilation, vasopressor, and inotropic support. Blood cultures and cultures of tracheal aspirate were positive for A. junii. After the microbiology sensitivities were known, antibiotic therapy was changed to meropenem, resulting in a good clinical outcome and resolution of infection. CONCLUSIONS: While A. junii is commonly a sensitive organism, there are reports of colistin and carbapenem resistance. It is important to document new presentations to expand our knowledge of this rare microorganism.https://www.infectiousjournal.com/wp-content/uploads/sites/6/2024/04/e1385-1.pdfacinetobacterbacteremiapneumonia |
| spellingShingle | F. Bartilotti Matos M. Ribeirinha A. Salgado A. Pereira Guedes C. Figueiredo A case of sepsis with multi-organ failure from a community-acquired Acinetobacter junii bacteremia in an immunocompetent patient Infectious Diseases and Tropical Medicine acinetobacter bacteremia pneumonia |
| title | A case of sepsis with multi-organ failure from a community-acquired Acinetobacter junii bacteremia in an immunocompetent patient |
| title_full | A case of sepsis with multi-organ failure from a community-acquired Acinetobacter junii bacteremia in an immunocompetent patient |
| title_fullStr | A case of sepsis with multi-organ failure from a community-acquired Acinetobacter junii bacteremia in an immunocompetent patient |
| title_full_unstemmed | A case of sepsis with multi-organ failure from a community-acquired Acinetobacter junii bacteremia in an immunocompetent patient |
| title_short | A case of sepsis with multi-organ failure from a community-acquired Acinetobacter junii bacteremia in an immunocompetent patient |
| title_sort | case of sepsis with multi organ failure from a community acquired acinetobacter junii bacteremia in an immunocompetent patient |
| topic | acinetobacter bacteremia pneumonia |
| url | https://www.infectiousjournal.com/wp-content/uploads/sites/6/2024/04/e1385-1.pdf |
| work_keys_str_mv | AT fbartilottimatos acaseofsepsiswithmultiorganfailurefromacommunityacquiredacinetobacterjuniibacteremiainanimmunocompetentpatient AT mribeirinha acaseofsepsiswithmultiorganfailurefromacommunityacquiredacinetobacterjuniibacteremiainanimmunocompetentpatient AT asalgado acaseofsepsiswithmultiorganfailurefromacommunityacquiredacinetobacterjuniibacteremiainanimmunocompetentpatient AT apereiraguedes acaseofsepsiswithmultiorganfailurefromacommunityacquiredacinetobacterjuniibacteremiainanimmunocompetentpatient AT cfigueiredo acaseofsepsiswithmultiorganfailurefromacommunityacquiredacinetobacterjuniibacteremiainanimmunocompetentpatient AT fbartilottimatos caseofsepsiswithmultiorganfailurefromacommunityacquiredacinetobacterjuniibacteremiainanimmunocompetentpatient AT mribeirinha caseofsepsiswithmultiorganfailurefromacommunityacquiredacinetobacterjuniibacteremiainanimmunocompetentpatient AT asalgado caseofsepsiswithmultiorganfailurefromacommunityacquiredacinetobacterjuniibacteremiainanimmunocompetentpatient AT apereiraguedes caseofsepsiswithmultiorganfailurefromacommunityacquiredacinetobacterjuniibacteremiainanimmunocompetentpatient AT cfigueiredo caseofsepsiswithmultiorganfailurefromacommunityacquiredacinetobacterjuniibacteremiainanimmunocompetentpatient |