Castleman's Disease: An Intrapulmonary Form with Intrafissural Development

Castleman's disease (CD) is an uncommon, mainly benign, lymphoproliferative disorder of unknown etiology, mostly involving the mediastinum. Parenchymal lung involvement of the disease is exceedingly rare. We describe a case of CD in a 23-year-old woman with a 4-year history of recurring dyspnea...

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Main Authors: Hajer Racil, Sana Cheikh Rouhou, Olfa Ismail, Saoussen Hantous-Zannad, Nawel Chaouch, Mourad Zarrouk, Belhassen Smati, Faouzi Mezni, Abdellatif Chabbou
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2009.110
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author Hajer Racil
Sana Cheikh Rouhou
Olfa Ismail
Saoussen Hantous-Zannad
Nawel Chaouch
Mourad Zarrouk
Belhassen Smati
Faouzi Mezni
Abdellatif Chabbou
author_facet Hajer Racil
Sana Cheikh Rouhou
Olfa Ismail
Saoussen Hantous-Zannad
Nawel Chaouch
Mourad Zarrouk
Belhassen Smati
Faouzi Mezni
Abdellatif Chabbou
author_sort Hajer Racil
collection DOAJ
description Castleman's disease (CD) is an uncommon, mainly benign, lymphoproliferative disorder of unknown etiology, mostly involving the mediastinum. Parenchymal lung involvement of the disease is exceedingly rare. We describe a case of CD in a 23-year-old woman with a 4-year history of recurring dyspnea and nonproductive cough, whose chest X-ray showed an abnormal shadow of the right hilum. Chest computed tomography confirmed the presence of a tissue-density mass of the right lower lobe, demonstrating poor contrast enhancement, associated with multiple laterotracheal and mediastinal lymphadenopathies. The patient underwent curative surgery, revealing a right hilar compressive mass, with an intrafissural development between the superior and middle lobes. Pneumonectomy was performed due to profuse bleeding. This case of CD is particular because of its unusual intrapulmonary location and its intrafissural development. Poor contrast enhancement is atypical in CD.
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issn 1537-744X
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publishDate 2009-01-01
publisher Wiley
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series The Scientific World Journal
spelling doaj-art-da5f7f716471466290e6042e57a5ec6b2025-08-20T02:21:25ZengWileyThe Scientific World Journal1537-744X2009-01-01994094510.1100/tsw.2009.110Castleman's Disease: An Intrapulmonary Form with Intrafissural DevelopmentHajer Racil0Sana Cheikh Rouhou1Olfa Ismail2Saoussen Hantous-Zannad3Nawel Chaouch4Mourad Zarrouk5Belhassen Smati6Faouzi Mezni7Abdellatif Chabbou8Pulmonology Department, Pavillon II, Abderrahman Mami Hospital, Ariana, TunisiaPulmonology Department, Pavillon II, Abderrahman Mami Hospital, Ariana, TunisiaPathology Department, Abderrahman Mami Hospital, Ariana, TunisiaRadiology Department, Abderrahman Mami Hospital, Ariana, TunisiaPulmonology Department, Pavillon II, Abderrahman Mami Hospital, Ariana, TunisiaPulmonology Department, Pavillon II, Abderrahman Mami Hospital, Ariana, TunisiaThoracic Surgery Department, Abderrahman Mami Hospital, Ariana, TunisiaPathology Department, Abderrahman Mami Hospital, Ariana, TunisiaPulmonology Department, Pavillon II, Abderrahman Mami Hospital, Ariana, TunisiaCastleman's disease (CD) is an uncommon, mainly benign, lymphoproliferative disorder of unknown etiology, mostly involving the mediastinum. Parenchymal lung involvement of the disease is exceedingly rare. We describe a case of CD in a 23-year-old woman with a 4-year history of recurring dyspnea and nonproductive cough, whose chest X-ray showed an abnormal shadow of the right hilum. Chest computed tomography confirmed the presence of a tissue-density mass of the right lower lobe, demonstrating poor contrast enhancement, associated with multiple laterotracheal and mediastinal lymphadenopathies. The patient underwent curative surgery, revealing a right hilar compressive mass, with an intrafissural development between the superior and middle lobes. Pneumonectomy was performed due to profuse bleeding. This case of CD is particular because of its unusual intrapulmonary location and its intrafissural development. Poor contrast enhancement is atypical in CD.http://dx.doi.org/10.1100/tsw.2009.110
spellingShingle Hajer Racil
Sana Cheikh Rouhou
Olfa Ismail
Saoussen Hantous-Zannad
Nawel Chaouch
Mourad Zarrouk
Belhassen Smati
Faouzi Mezni
Abdellatif Chabbou
Castleman's Disease: An Intrapulmonary Form with Intrafissural Development
The Scientific World Journal
title Castleman's Disease: An Intrapulmonary Form with Intrafissural Development
title_full Castleman's Disease: An Intrapulmonary Form with Intrafissural Development
title_fullStr Castleman's Disease: An Intrapulmonary Form with Intrafissural Development
title_full_unstemmed Castleman's Disease: An Intrapulmonary Form with Intrafissural Development
title_short Castleman's Disease: An Intrapulmonary Form with Intrafissural Development
title_sort castleman s disease an intrapulmonary form with intrafissural development
url http://dx.doi.org/10.1100/tsw.2009.110
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