Bullous Systemic Lupus Erythematosus Associated with Esophagitis Dissecans Superficialis

Bullous systemic lupus erythematosus is one of the rare autoantibody mediated skin manifestation of systemic lupus erythematosus (SLE) demonstrating subepidermal blistering with neutrophilic infiltrate histologically. We present a case of a 40-year-old Hispanic female who presented with a several mo...

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Main Authors: Meera Yogarajah, Bhradeev Sivasambu, Eric A. Jaffe
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Rheumatology
Online Access:http://dx.doi.org/10.1155/2015/930683
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author Meera Yogarajah
Bhradeev Sivasambu
Eric A. Jaffe
author_facet Meera Yogarajah
Bhradeev Sivasambu
Eric A. Jaffe
author_sort Meera Yogarajah
collection DOAJ
description Bullous systemic lupus erythematosus is one of the rare autoantibody mediated skin manifestation of systemic lupus erythematosus (SLE) demonstrating subepidermal blistering with neutrophilic infiltrate histologically. We present a case of a 40-year-old Hispanic female who presented with a several months’ history of multiple blistering pruritic skin lesions involving the face and trunk, a photosensitive rash over the face and neck, swelling of the right neck lymph node, and joint pain involving her elbows and wrist. Her malady was diagnosed as bullous systemic lupus erythematosus based on the immunological workup and biopsy of her skin lesions. The patient also complained of odynophagia and endoscopy revealed esophagitis dissecans superficialis which is a rare endoscopic finding characterized by sloughing of the esophageal mucosa. The bullous disorders typically associated with esophagitis dissecans superficialis are pemphigus and rarely bullous pemphigoid. However, this is the first reported case of bullous systemic lupus erythematosus associated with esophagitis dissecans superficialis.
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spelling doaj-art-da5955868bfa47af85b0694c747e7ce92025-08-20T02:21:25ZengWileyCase Reports in Rheumatology2090-68892090-68972015-01-01201510.1155/2015/930683930683Bullous Systemic Lupus Erythematosus Associated with Esophagitis Dissecans SuperficialisMeera Yogarajah0Bhradeev Sivasambu1Eric A. Jaffe2Department of Medicine, Interfaith Medical Center, Brooklyn, NY 11213, USADepartment of Medicine, Interfaith Medical Center, Brooklyn, NY 11213, USADepartment of Medicine, Interfaith Medical Center, Brooklyn, NY 11213, USABullous systemic lupus erythematosus is one of the rare autoantibody mediated skin manifestation of systemic lupus erythematosus (SLE) demonstrating subepidermal blistering with neutrophilic infiltrate histologically. We present a case of a 40-year-old Hispanic female who presented with a several months’ history of multiple blistering pruritic skin lesions involving the face and trunk, a photosensitive rash over the face and neck, swelling of the right neck lymph node, and joint pain involving her elbows and wrist. Her malady was diagnosed as bullous systemic lupus erythematosus based on the immunological workup and biopsy of her skin lesions. The patient also complained of odynophagia and endoscopy revealed esophagitis dissecans superficialis which is a rare endoscopic finding characterized by sloughing of the esophageal mucosa. The bullous disorders typically associated with esophagitis dissecans superficialis are pemphigus and rarely bullous pemphigoid. However, this is the first reported case of bullous systemic lupus erythematosus associated with esophagitis dissecans superficialis.http://dx.doi.org/10.1155/2015/930683
spellingShingle Meera Yogarajah
Bhradeev Sivasambu
Eric A. Jaffe
Bullous Systemic Lupus Erythematosus Associated with Esophagitis Dissecans Superficialis
Case Reports in Rheumatology
title Bullous Systemic Lupus Erythematosus Associated with Esophagitis Dissecans Superficialis
title_full Bullous Systemic Lupus Erythematosus Associated with Esophagitis Dissecans Superficialis
title_fullStr Bullous Systemic Lupus Erythematosus Associated with Esophagitis Dissecans Superficialis
title_full_unstemmed Bullous Systemic Lupus Erythematosus Associated with Esophagitis Dissecans Superficialis
title_short Bullous Systemic Lupus Erythematosus Associated with Esophagitis Dissecans Superficialis
title_sort bullous systemic lupus erythematosus associated with esophagitis dissecans superficialis
url http://dx.doi.org/10.1155/2015/930683
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AT ericajaffe bulloussystemiclupuserythematosusassociatedwithesophagitisdissecanssuperficialis