Phase-transfer catalysis for synthesis of ethyl 2-(4-nitrophenoxy)acetate under sonication- kinetic aspects

Ultrasound assisted phase-transfer catalyzed preparation of ethyl 2-(4-nitrophenoxy)acetate from the corresponding p-nitrophenol and ethyl 2-bromoacetate using the mild solid base, anhydrous potassium carbonate, under very mild conditions is reported. The solid-liquid reactions were performed in a b...

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Main Authors: V. Rajendran, P. Abimannan
Format: Article
Language:English
Published: Iranian Association of Chemical Engineering (IAChE) 2016-04-01
Series:Iranian Journal of Chemical Engineering
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Online Access:https://www.ijche.com/article_15371_e041af6a2dc670d7b0ab84c7f1bc84e9.pdf
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author V. Rajendran
P. Abimannan
author_facet V. Rajendran
P. Abimannan
author_sort V. Rajendran
collection DOAJ
description Ultrasound assisted phase-transfer catalyzed preparation of ethyl 2-(4-nitrophenoxy)acetate from the corresponding p-nitrophenol and ethyl 2-bromoacetate using the mild solid base, anhydrous potassium carbonate, under very mild conditions is reported. The solid-liquid reactions were performed in a batch reactor equipped with reflux condenser, and ultrasonic irradiations were introduced using an ultrasonic bath operating at a frequency of 28 kHz with a power rating of 300 W. The reaction was carried out at 50°C under pseudo-first order conditions and was monitored by gas chromatography (GC). From the experimental data, a rate expression had been developed to explain the kinetic behavior of the reaction from which the apparent rate constant (kapp) of the organic phase was attained. The effects of different operating parameters such as stirring rate, temperature, catalyst loading and kind of Phase-transfer catalysts, base variation and quantity of water, kind of solvents have been investigated to maximize the yield of synthesis of ethyl 2-(4-nitrophenoxy)acetate.
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publishDate 2016-04-01
publisher Iranian Association of Chemical Engineering (IAChE)
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spelling doaj-art-da50c922ccf9482fabe021d8e71fcb7c2025-08-20T03:13:38ZengIranian Association of Chemical Engineering (IAChE)Iranian Journal of Chemical Engineering1735-53972008-23552016-04-01132808715371Phase-transfer catalysis for synthesis of ethyl 2-(4-nitrophenoxy)acetate under sonication- kinetic aspectsV. Rajendran0P. Abimannan1Pachaiyappa’s College for Men, Kanchipuram, Tamil Nadu, India – 631 501Pachaiyappa’s College for Men, Kanchipuram, Tamil Nadu, India – 631 501Ultrasound assisted phase-transfer catalyzed preparation of ethyl 2-(4-nitrophenoxy)acetate from the corresponding p-nitrophenol and ethyl 2-bromoacetate using the mild solid base, anhydrous potassium carbonate, under very mild conditions is reported. The solid-liquid reactions were performed in a batch reactor equipped with reflux condenser, and ultrasonic irradiations were introduced using an ultrasonic bath operating at a frequency of 28 kHz with a power rating of 300 W. The reaction was carried out at 50°C under pseudo-first order conditions and was monitored by gas chromatography (GC). From the experimental data, a rate expression had been developed to explain the kinetic behavior of the reaction from which the apparent rate constant (kapp) of the organic phase was attained. The effects of different operating parameters such as stirring rate, temperature, catalyst loading and kind of Phase-transfer catalysts, base variation and quantity of water, kind of solvents have been investigated to maximize the yield of synthesis of ethyl 2-(4-nitrophenoxy)acetate.https://www.ijche.com/article_15371_e041af6a2dc670d7b0ab84c7f1bc84e9.pdfsolid-liquid ptcp-nitrophenolsonocatalysisethyl 2-bromoacetatechemical kinetics
spellingShingle V. Rajendran
P. Abimannan
Phase-transfer catalysis for synthesis of ethyl 2-(4-nitrophenoxy)acetate under sonication- kinetic aspects
Iranian Journal of Chemical Engineering
solid-liquid ptc
p-nitrophenol
sonocatalysis
ethyl 2-bromoacetate
chemical kinetics
title Phase-transfer catalysis for synthesis of ethyl 2-(4-nitrophenoxy)acetate under sonication- kinetic aspects
title_full Phase-transfer catalysis for synthesis of ethyl 2-(4-nitrophenoxy)acetate under sonication- kinetic aspects
title_fullStr Phase-transfer catalysis for synthesis of ethyl 2-(4-nitrophenoxy)acetate under sonication- kinetic aspects
title_full_unstemmed Phase-transfer catalysis for synthesis of ethyl 2-(4-nitrophenoxy)acetate under sonication- kinetic aspects
title_short Phase-transfer catalysis for synthesis of ethyl 2-(4-nitrophenoxy)acetate under sonication- kinetic aspects
title_sort phase transfer catalysis for synthesis of ethyl 2 4 nitrophenoxy acetate under sonication kinetic aspects
topic solid-liquid ptc
p-nitrophenol
sonocatalysis
ethyl 2-bromoacetate
chemical kinetics
url https://www.ijche.com/article_15371_e041af6a2dc670d7b0ab84c7f1bc84e9.pdf
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AT pabimannan phasetransfercatalysisforsynthesisofethyl24nitrophenoxyacetateundersonicationkineticaspects