Preliminary insights into serum metabolomics in atrophic myopic maculopathy: potential link to fatty acid metabolism dysregulation

Preliminary insights into serum metabolomics in atrophic myopic maculopathy: potential link to fatty acid metabolism dysregulation

Abstract Introduction: Atrophic myopic maculopathy (AMM) causes irreversible and progressive visual impairment. Metabolomics offers a valuable opportunity for exploring the pathological mechanisms of AMM and identifying potential therapeutic targets. This study compared serum metabolite profiles bet...

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Bibliographic Details
Main Authors: Yuanyuan Fan, Bintao Xie, Lifeng Chen, Mengai Wu, Li Lin, Zhijie Wang, Bin Zheng
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Ophthalmology
Subjects:
Atrophic myopic maculopathy
Untargeted metabolomics
Fatty acid metabolism
Mitochondrial dysfunction
Inflammation
Online Access:https://doi.org/10.1186/s12886-025-04220-7
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