Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Presenting as Chronic Diarrhea; An Unusual Presentation of a Common Lymphoproliferative Disorder
Chronic lymphocytic leukemia (CLL) is the most common lymphoproliferative disorder in the United States. It has a variable presentation with most patients having asymptomatic lymphocytosis. Many other patients present with lymphadenopathy or enlargement of other organs of the reticuloendothelial sys...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Gastrointestinal Medicine |
| Online Access: | http://dx.doi.org/10.1155/2021/8884820 |
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| author | Smitha Narayana Gowda Hafez Mohammad Abdullah Rakshya Sharma Mohamed A. Abdallah |
| author_facet | Smitha Narayana Gowda Hafez Mohammad Abdullah Rakshya Sharma Mohamed A. Abdallah |
| author_sort | Smitha Narayana Gowda |
| collection | DOAJ |
| description | Chronic lymphocytic leukemia (CLL) is the most common lymphoproliferative disorder in the United States. It has a variable presentation with most patients having asymptomatic lymphocytosis. Many other patients present with lymphadenopathy or enlargement of other organs of the reticuloendothelial system. However, CLL can present with extramedullary involvement. Most commonly, this is in the form of skin or central nervous system involvement, though rarely it can present with gastrointestinal involvement. Here, we present the case of a 70-year-old Caucasian male who presented with chronic diarrhea for over 4 months. After failing conservative treatment, a colonoscopy was performed which showed diffuse mucosal nodularities with a biopsy revealing CLL. The patient was treated successfully with chemotherapy and his diarrhea improved. This is a differential to keep in mind in patients with chronic diarrhea, once the more common causes have been ruled out. |
| format | Article |
| id | doaj-art-da4378842e0446c2b1da3c888e4fd030 |
| institution | OA Journals |
| issn | 2090-6528 2090-6536 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Gastrointestinal Medicine |
| spelling | doaj-art-da4378842e0446c2b1da3c888e4fd0302025-08-20T02:21:11ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362021-01-01202110.1155/2021/88848208884820Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Presenting as Chronic Diarrhea; An Unusual Presentation of a Common Lymphoproliferative DisorderSmitha Narayana Gowda0Hafez Mohammad Abdullah1Rakshya Sharma2Mohamed A. Abdallah3Department of Internal Medicine, University of South Dakota Sanford School of Medicine, Sioux Falls, SD, USADepartment of Internal Medicine, University of South Dakota Sanford School of Medicine, Sioux Falls, SD, USADepartment of Internal Medicine, University of South Dakota Sanford School of Medicine, Sioux Falls, SD, USADepartment of Pulmonary Medicine, University of South Dakota Sanford School of Medicine, Sioux Falls, SD, USAChronic lymphocytic leukemia (CLL) is the most common lymphoproliferative disorder in the United States. It has a variable presentation with most patients having asymptomatic lymphocytosis. Many other patients present with lymphadenopathy or enlargement of other organs of the reticuloendothelial system. However, CLL can present with extramedullary involvement. Most commonly, this is in the form of skin or central nervous system involvement, though rarely it can present with gastrointestinal involvement. Here, we present the case of a 70-year-old Caucasian male who presented with chronic diarrhea for over 4 months. After failing conservative treatment, a colonoscopy was performed which showed diffuse mucosal nodularities with a biopsy revealing CLL. The patient was treated successfully with chemotherapy and his diarrhea improved. This is a differential to keep in mind in patients with chronic diarrhea, once the more common causes have been ruled out.http://dx.doi.org/10.1155/2021/8884820 |
| spellingShingle | Smitha Narayana Gowda Hafez Mohammad Abdullah Rakshya Sharma Mohamed A. Abdallah Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Presenting as Chronic Diarrhea; An Unusual Presentation of a Common Lymphoproliferative Disorder Case Reports in Gastrointestinal Medicine |
| title | Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Presenting as Chronic Diarrhea; An Unusual Presentation of a Common Lymphoproliferative Disorder |
| title_full | Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Presenting as Chronic Diarrhea; An Unusual Presentation of a Common Lymphoproliferative Disorder |
| title_fullStr | Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Presenting as Chronic Diarrhea; An Unusual Presentation of a Common Lymphoproliferative Disorder |
| title_full_unstemmed | Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Presenting as Chronic Diarrhea; An Unusual Presentation of a Common Lymphoproliferative Disorder |
| title_short | Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Presenting as Chronic Diarrhea; An Unusual Presentation of a Common Lymphoproliferative Disorder |
| title_sort | chronic lymphocytic leukemia small lymphocytic lymphoma presenting as chronic diarrhea an unusual presentation of a common lymphoproliferative disorder |
| url | http://dx.doi.org/10.1155/2021/8884820 |
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