The Direct Healthcare Expenditures of Prostate Cancer by Disease Severity: Evidence from US National Survey Data
**Background:** In the United States, approximately 2.8 million men have a history of prostate cancer (PC). **Objective:** This study quantified the effects of PC, overall and by disease severity on direct healthcare costs to insurers and patients. **Methods:** Using 1996–2010 data from the Medica...
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| Format: | Article |
| Language: | English |
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Columbia Data Analytics, LLC
2016-10-01
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| Series: | Journal of Health Economics and Outcomes Research |
| Online Access: | https://doi.org/10.36469/9844 |
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| author | Peter J. Mallow Jie Chen John A. Rizzo John R. Penrod Geralyn C. Trudel Teresa M. Zyczynski |
| author_facet | Peter J. Mallow Jie Chen John A. Rizzo John R. Penrod Geralyn C. Trudel Teresa M. Zyczynski |
| author_sort | Peter J. Mallow |
| collection | DOAJ |
| description | **Background:** In the United States, approximately 2.8 million men have a history of prostate cancer (PC).
**Objective:** This study quantified the effects of PC, overall and by disease severity on direct healthcare costs to insurers and patients.
**Methods:** Using 1996–2010 data from the Medical Expenditure Panel Survey (MEPS), a large, nationally representative US database, multivariate analyses were used to assess the relationship between PC and direct annual healthcare costs to insurers and patients, at individual and US aggregate levels. Men aged 40 years and older with International Classification of Diseases, Ninth Revision (ICD-9) diagnosis code 185 were identified. Disease severity was determined with clinical assistance and based, in part, on the data in MEPS. The cohorts were: localized cancer not treated with chemotherapy, localized cancer treated with chemotherapy, and metastatic cancer.
**Results:** The MEPS database included 1297 patients with PC: 811 patients with localized PC not treated with chemotherapy, 426 patients with PC treated with chemotherapy, and 60 patients with metastatic PC. PC had a larger effect on incremental costs for metastatic patients, $20 357, vs $16 709 for localized PC with chemotherapy, and $5238 for localized PC with no chemotherapy. When aggregated to the US population, PC accounted for an incremental annual cost of $15 billion. The largest aggregate annual costs were incurred by patients with localized PC treated with chemotherapy ($8.6 billion), compared to those not treated with chemotherapy ($4.8 billion) and metastatic patients ($1.6 billion).
**Conclusions:** The aggregate annual costs of PC are substantial for all groups examined and greatest for patients with localized cancer treated with chemotherapy. This reflects the relatively high prevalence and high per capita healthcare expenditures associated with this group. With a growing and aging population, the prevalence of PC is expected to rise, increasing the burden on public health. |
| format | Article |
| id | doaj-art-da3f11351f10499d88dfdebfc911923d |
| institution | Kabale University |
| issn | 2327-2236 |
| language | English |
| publishDate | 2016-10-01 |
| publisher | Columbia Data Analytics, LLC |
| record_format | Article |
| series | Journal of Health Economics and Outcomes Research |
| spelling | doaj-art-da3f11351f10499d88dfdebfc911923d2025-02-10T16:12:34ZengColumbia Data Analytics, LLCJournal of Health Economics and Outcomes Research2327-22362016-10-0131The Direct Healthcare Expenditures of Prostate Cancer by Disease Severity: Evidence from US National Survey DataPeter J. MallowJie ChenJohn A. RizzoJohn R. PenrodGeralyn C. TrudelTeresa M. Zyczynski**Background:** In the United States, approximately 2.8 million men have a history of prostate cancer (PC). **Objective:** This study quantified the effects of PC, overall and by disease severity on direct healthcare costs to insurers and patients. **Methods:** Using 1996–2010 data from the Medical Expenditure Panel Survey (MEPS), a large, nationally representative US database, multivariate analyses were used to assess the relationship between PC and direct annual healthcare costs to insurers and patients, at individual and US aggregate levels. Men aged 40 years and older with International Classification of Diseases, Ninth Revision (ICD-9) diagnosis code 185 were identified. Disease severity was determined with clinical assistance and based, in part, on the data in MEPS. The cohorts were: localized cancer not treated with chemotherapy, localized cancer treated with chemotherapy, and metastatic cancer. **Results:** The MEPS database included 1297 patients with PC: 811 patients with localized PC not treated with chemotherapy, 426 patients with PC treated with chemotherapy, and 60 patients with metastatic PC. PC had a larger effect on incremental costs for metastatic patients, $20 357, vs $16 709 for localized PC with chemotherapy, and $5238 for localized PC with no chemotherapy. When aggregated to the US population, PC accounted for an incremental annual cost of $15 billion. The largest aggregate annual costs were incurred by patients with localized PC treated with chemotherapy ($8.6 billion), compared to those not treated with chemotherapy ($4.8 billion) and metastatic patients ($1.6 billion). **Conclusions:** The aggregate annual costs of PC are substantial for all groups examined and greatest for patients with localized cancer treated with chemotherapy. This reflects the relatively high prevalence and high per capita healthcare expenditures associated with this group. With a growing and aging population, the prevalence of PC is expected to rise, increasing the burden on public health.https://doi.org/10.36469/9844 |
| spellingShingle | Peter J. Mallow Jie Chen John A. Rizzo John R. Penrod Geralyn C. Trudel Teresa M. Zyczynski The Direct Healthcare Expenditures of Prostate Cancer by Disease Severity: Evidence from US National Survey Data Journal of Health Economics and Outcomes Research |
| title | The Direct Healthcare Expenditures of Prostate Cancer by Disease Severity: Evidence from US National Survey Data |
| title_full | The Direct Healthcare Expenditures of Prostate Cancer by Disease Severity: Evidence from US National Survey Data |
| title_fullStr | The Direct Healthcare Expenditures of Prostate Cancer by Disease Severity: Evidence from US National Survey Data |
| title_full_unstemmed | The Direct Healthcare Expenditures of Prostate Cancer by Disease Severity: Evidence from US National Survey Data |
| title_short | The Direct Healthcare Expenditures of Prostate Cancer by Disease Severity: Evidence from US National Survey Data |
| title_sort | direct healthcare expenditures of prostate cancer by disease severity evidence from us national survey data |
| url | https://doi.org/10.36469/9844 |
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